Principal Scientist - In Vitro Biology & Pharmacology

Requirements

• Ph.D. in Biochemistry, Pharmacology, In Vitro Biology, or a related field, with at least 8 years of post-Ph.D. experience
• Strong scientific background in metabolism and/or obesity biology
• Experience supporting drug discovery and/or drug development projects
• Extensive experience with in vitro/ex vivo biological models, including primary cells and cell-based readouts
• Experience with G-protein coupled receptor (GPCR) pharmacology (advantageous)
• Experience working with external vendors and contract research organizations (CROs) (advantageous)
• Your new team
• Let's bond and be bold
• We have a unique culture, characterized by excellent teamwork and strong engagement across the organization. And we want you to help us strengthen this culture.
• Interested in bonding with us? Then please apply no later than June 19, 2026 , or as soon as possible. The applications will be reviewed as they come in. While a cover letter is not required, please include a few sentences in your CV explaining your motivation for applying.
• For further information, please contact Head of In Vitro Biology , Gitte Lund Christensen and GLChristensen@zealandpharma.com
• We are committed to an inclusive recruitment process and welcome applications from all job applicants.
• About Zealand Pharma A/S

Benefits

Additional Information

Does it excite you to work with cell-based disease models that advance peptide-based medicines for obesity and metabolic health , and do you have experience with in vitro biology, pharmacology and mechanism-of-action studies ? If this sounds like you, and you are ready to take on a broad area of responsibilities, then you could be our new colleague. Your new position As Principal Scientist - In Vitro Biology & Pharmacology, you will play a central role in driving research projects and advancing biological understanding of peptide-based drug candidates within metabolism and obesity. The position offers a unique opportunity to shape scientific approaches and deepen insight into tissue-specific mechanisms of action. You will work cross-functionally to translate biology into robust preclinical hypotheses and decision-ready data that supports progression of candidates. We offer exciting responsibilities: Contribute centrally to one or more research projects from idea generation through preclinical validation Translate mechanism-of-action knowledge into testable preclinical hypotheses, endpoints, and measurable success criteria Develop and define in vitro biological models relevant to obesity pharmacology Drive in vitro disease-model studies to characterize molecular candidates and support data-driven selection of lead compounds Analyze and interpret complex data spanning pharmacology profiling and cell biology and communicate recommendations to senior leadership and external partners Ensure robust study design, documentation, and clear data packages that enable efficient decision-making and transitions to in vivo evaluation Your profile You are a collaborative and curious scientist who enjoys staying up to date with disease-relevant science and actively driving scientific discussions with colleagues at all levels. You bring broad knowledge of obesity-related biology and hands-on experience building in vitro disease models to investigate mechanism-of-action questions. You thrive in a dynamic environment, communicate clearly, and are motivated by making a meaningful impact on patient-relevant science.

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