Biomarker Scientist - LCMS
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Requirements
- Experience with LC-MS in proteomics workflows.
- Familiarity with automated liquid handlers, Thermo Orbitrap instruments, or Sciex triple quadrupole platforms.
- Authorization to work in the United States indefinitely without restriction or sponsorship.
- The position is full-time, Monday-Friday, 8am-5pm with overtime as needed. Candidates living within a commutable distance of Boston, MA are encouraged to apply.
- Excellent full-time benefits include:
- Comprehensive medical coverage, dental, and vision options
- Life and disability insurance
- 401(k) with company match
- Paid vacation and holidays
- Eligibility for yearly goal-based bonus & merit-based increases
- Compensation: $31.00-$41.00 per hour based on education and related experience.
- Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.
Benefits
Additional Information
The position will support a Neuroscience Biomarks client team that is responsible for LC-MS-based proteomics to identify and quantify biomarkers associated with neurodegenerative diseases, including Alzheimer's Disease, Parkinson's Disease, and Amyotrophic Lateral Sclerosis. We are looking for a motivated scientist eager to gain hands-on experience in LC-MS proteomics workflows applied to CSF, plasma, and tissue biomarker studies, and to grow their technical skills in a collaborative, fast-moving research environment. Principal responsibilities will include weekly and monthly lab operations tasks (approximately 70% effort) while additional responsibilities will include routine testing (approximately 30% effort). Job Responsibilities and Requirements Lab Operations: Manage lab instruments, consumables, and chemicals/reagents. Manage lab supply and reagent inventory, including aliquoting, ordering, and stocking. Perform sample management, including sorting, storage, and manifest recording in Benchling (ELN). Prepare reagents and solutions for proteomics and biochemistry workflows. Coordinate with the facilities team to manage instrument servicing and preventive maintenance schedules. Analytical Testing: Perform biochemistry assays, including sample preparation and Western Blotting using human or animal biospecimen. Perform LC-MS support tasks including instrument source cleaning, monthly QC runs, mobile phase and buffer preparation, and sample injection on Thermo Orbitrap and Sciex triple quadrupole platforms. Process and analyze data generated from biochemistry and LC-MS assays. under scientist supervision and contribute to summarizing and reporting findings. Maintain accurate and detailed records in the electronic laboratory notebook (ELN). Basic Minimum Qualifications: B.S. in Biochemistry, Molecular Biology, Biotechnology, Immunology, Neuroscience, or related field with at least 2 years of LCMS experience in the pharmaceutical industry including setup, cleaning, and monthly QC runs. Demonstrated hands-on experience with biochemistry and molecular biology techniques, including protein sample preparation, Western Blotting, and buffer preparation. Ability to follow and troubleshoot established laboratory protocols independently after training, including identifying and escalating reagent, instrument, or assay issues.
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