Clinical Engagement Lead - South / Southeast

About the role

About Beeline Medicines: Beeline Medicines is a clinical‑stage biotechnology company focused on developing and delivering category-leading precision therapies to transform the lives of people living with autoimmune and inflammatory diseases. With a portfolio of potential best-in-class and first-in-disease therapeutic candidates that directly target key pathways governing dysregulated immunological and inflammatory responses, the Company is developing medicines that have the opportunity to provide durable, life-changing impact. Led by an established executive team and backed by world-class life science investors, each day Beeline Medicines is determined to bring the scientific rigor and operational excellence to get to what matters for patients - realizing a world where people with immune-mediated diseases can live life fully. Job Summary: The Clinical Engagement Lead, US is a field-based is a senior level, site facing clinical development professional responsible for building and managing investigator and site relationships across the globe in support of the organization's clinical trial portfolio. This role serves as the primary site-facing liaison between the organization and its global clinical investigators, academic medical centers, and research sites - supporting site identification, investigator engagement, and clinical trial execution to position the organization's I&I programs competitively in the clinical research landscape. The Clinical Engagement Lead combines knowledge of the I&I therapeutic area with strong relationship management skills and a thorough understanding of clinical trial operations - serving as a trusted partner to investigators and a critical field intelligence link back to the internal Clinical Development and Medical Affairs teams. This is a highly visible, externally focused role that requires the ability to represent the organization's science with authority, build lasting relationships with leading clinical researchers, and operate independently across a broad assigned geography. Work Arrangement & Location: Field-Based - This position is field-based, and the incumbent will be expected to work within their assigned territory or region on behalf of the company. Regular travel within the designated geography is an inherent requirement of this role. Additional travel outside of the assigned territory may be required based on business need, including attendance at company meetings, training, or other organizational events. Territory Assignment Notice: AL, AR, FL, GA, KY, LA, MO, MS, NC, OK, SC, TN, TX, VA, WV Notice: The geographic territory outlined for this position reflects current business needs and is subject to change at the discretion of the organization. Territory boundaries, state assignments, and regional alignments may be modified at any time based on evolving business priorities, organizational restructuring, or strategic initiatives. The selected candidate will be expected to adapt to any such changes as a condition of employment. Essential Duties and Responsibilities: Build and manage a portfolio of region/country investigator and clinical site relationships in the I&I therapeutic area - identifying, engaging, and developing long-term partnerships with principal investigators, academic medical centers, community research sites, and subspecialty practices relevant to Beeline's clinical programs. Lead site identification and feasibility activities for clinical trials - conducting operational site assessments, evaluating investigator interest and patient population access, and providing strategic recommendations to Clinical Development and Clinical Operations on site selection and activation. Serve as the primary clinical liaison to regional/country level investigators - facilitating peer-to-peer scientific exchange on Beeline's pipeline, conducting protocol discussions, supporting site initiation and training, and maintaining ongoing engagement with investigators throughout the trial lifecycle. Support clinical trial enrollment and retention at region/country sites - working proactively with investigators and site staff to identify enrollment challenges, implement site-level solutions, and maintain site motivation and engagement across all active Beeline studies. Capture and communicate region/country clinical landscape intelligence - including investigator perspectives, competitive trial activity, site capacity trends, and unmet medical need insights - back to Clinical Development, Medical Affairs, and Commercial teams in a structured, actionable manner. Partner with Medical Affairs MSLs to ensure coordination and alignment of scientific engagement activities at the investigator level - establishing clear boundaries between clinical trial support and medical affairs activities and collaborating to maximize the impact of both. Represent organization clinical and scientific meetings, investigator symposia, disease-area conferences, and site visits - en

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