Vice President, Medical Affairs

Requirements

• Advanced degree in life sciences, medicine, or a related field required (MD, PharmD, PhD preferred) with 10+ years of industry experience
• Significant Medical Affairs leadership experience in biotechnology or pharmaceuticals, with demonstrated progression in scope and responsibility
• Deep expertise in scientific communications, external expert engagement, medical strategy, and cross-functional collaboration
• Experience building or scaling Medical Affairs capabilities in a growth-stage organization, especially on transitioning from clinical stage to commercialization, is strongly preferred
• Strong executive presence with excellent written and verbal communication skills and the ability to influence senior internal and external stakeholders
• Ability to operate strategically while remaining hands-on in a fast-paced, evolving environment
• Experience with real world datasets and studies
• A working knowledge of how to incorporate artificial intelligence and machine learning principles into medical affairs

Additional Information

Role Summary The Vice President, Medical Affairs will provide enterprise-level leadership across Lexeo's gene therapy program. Reporting to the Chief Medical Officer, this role will set the strategic direction for Medical Affairs, overseeing scientific communications, congress strategy, external expert engagement, medical information, medical evidence generation and medical education. This individual will serve as a senior cross-functional leader and strategic partner to Clinical Development, Regulatory, and Patient Advocacy teams. In this role, they will shape and scale the Medical Affairs function, build organizational capabilities, and drive external scientific leadership in support of Lexeo's development and future commercialization objectives. The ideal candidate is a strategic, hands-on leader who thrives in a dynamic, high-growth environment and can influence across the organization and external stakeholders. About Lexeo Lexeo Therapeutics is a clinical-stage genetic medicine company headquartered in New York City, pioneering cardiac genetic medicine candidates to treat the root causes of inherited cardiovascular diseases. Our lead program, LX2006, targets cardiomyopathy associated with Friedreich's Ataxia and anchors a broader pipeline addressing genetically defined conditions such as hypertrophic and arrhythmogenic cardiomyopathies. Backed by a strong financial foundation, Lexeo is positioned to translate groundbreaking science into durable clinical impact. Our work culture is a hybrid model with 2 days/week in the New York City office and 3 days working from home. Lexeo Therapeutics is an EEO employer committed to an exciting, diverse, and enriching work environment.

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