Research Specialist A/B

Requirements

• Research Specialist A
• Bachelor of Science and 0 to 1 year of experience or equivalent combination of education and experience is required.
• Research Specialist B
• Bachelor of Science and 1 to 2 years of experience or equivalent combination of education and experience is required.
• Preferred:
• Research Specialist A:
• Basic computational skills in R and/or Python
• Have working knowledge of tissue culture and flow cytometry to be able to perform T cell stimulation, antibody staining, and FACS analyses.
• Solid understanding of adaptive immunity, especially T cell biology
• Strong communication skills and ability to work effectively in a collaborative team environment
• Excellent organizational skills and attention to detail
• Job Location - City, State
• Philadelphia, Pennsylvania
• Department / School
• Perelman School of Medicine
• Pay Range

Benefits

Additional Information

University Overview The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn's distinctive interdisciplinary approach to scholarship and learning. As an employer Penn has been ranked nationally on many occasions with the most recent award from Forbes who named Penn one of America's Best Large Employers in 2023. Penn offers a unique working environment within the city of Philadelphia. The University is situated on a beautiful urban campus, with easy access to a range of educational, cultural, and recreational activities. With its historical significance and landmarks, lively cultural offerings, and wide variety of atmospheres, Philadelphia is the perfect place to call home for work and play. The University offers a competitive benefits package that includes excellent healthcare and tuition benefits for employees and their families, generous retirement benefits, a wide variety of professional development opportunities, supportive work and family benefits, a wealth of health and wellness programs and resources, and much more. Posted Job Title Research Specialist A/B Job Profile Title Research Specialist A Job Description Summary We are seeking a highly motivated and enthusiastic individual with a strong background in computational biology to join our team. The successful candidate will contribute to publication-driven projects focused on understanding immune dysregulation in autoimmune diseases and identifying novel biomarkers for type 1 diabetes (T1D). Responsibilities include T cell stimulation, antibody staining, cell sorting, constructing bulk and single-cell sequencing libraries, performing RNA-seq, antibody-seq, TCR-seq, and BCR-seq data analyses and integration using R or Python. The ideal candidate will have experience with flow cytometry, track records of bulk and single-cell RNA, TCR, and BCR sequencing data analysis, proficiency in advanced quantitative statistical methods, and a solid understanding of adaptive immunity, particularly T cell biology. Strong communication and organizational skills are essential, and the ability to work collaboratively within a team is critical. This position offers a high degree of independence, opportunities for project leadership, and the chance to contribute to cutting-edge translational immunology research in a supportive and collaborative environment. Job Description Job Responsibilities Research Specialist A: Perform blood/tissue sample processing and assist with sample management Maintain cells in culture and perform T cell stimulation Perform antibody staining and analyses of cells on flow cytometer Assist with preparation of sequencing libraries and coordinate sample submission for sequencing Perform data preprocessing, batch effect correction, and basic analyses of sequencing data. Research Specialist B In addition to the duties outlined under Research Specialist A, Research Specialist B will be able to independently sort cells and prepare sequencing libraries. Will also carry out advanced downstream analyses of RNA, antibody, TCR, and BCR sequencing datasets. Position Contingent Upon Funding

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