Research Fellow in Translational Biology
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About the role
Would you like to work with cutting-edge preclinical models? Would you like to make a difference to how Central Nervous System therapeutics are developed? Can you provide technical input to research projects and do you have extensive laboratory and preclinical animal experience which includes skills in cancer? Blood-brain barrier (BBB) biology remains a significant challenge in brain physiology, disease, and treatment due to its complexity. We will examine whether 3D assembloids, derived from cardiac-like, vascular-like, and brain-like structures, can more authentically model the human BBB and neurovascular unit. This pioneering approach utilizes induced pluripotent stem cells in order to induce the formation of a human-like BBB and accurately replicate its natural development in vitro. This strategy is highly promising for gaining new insights into BBB development, and for advancing therapeutic delivery methods across the BBB. We're seeking candidates with expertise in preclinical modelling, particularly focusing on stem cell differentiation and organoid biology. What we offer in return 26 days holiday plus approx.16 Bank Holidays/days that the University is closed by custom (including Christmas) - That's 42 days a year! Generous pension scheme options plus life assurance Health and Wellbeing: Discounted staff membership options at The Edge, our state-of-the-art Campus gym, with a pool, sauna, climbing wall, cycle circuit, and sports halls. Personal Development: Access to courses run by our Organisational Development & Professional Learning team. All FMH staff are entitled to ten days staff development per year (pro rata). Please speak to your Line Manager about how you can utilise these Access to on-site childcare, shopping discounts and travel schemes are also available. And much more! If you are looking for a role that will be a part of a dynamic and committed team that aims to transform outcomes for brain cancer patients, apply today. To explore the post further or for any queries you may have, please contact: Heiko Wurdak, Associate Professor Email: h.wurdak@leeds.ac.uk £41,064 to £48,822 per annum (Grade 7)
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