Sr Associate Scientist I or II, GPCR Biology

Responsibilities

• Work closely with the Biology group to independently conceptualize, design and conduct in vitro studies aimed at supporting hit to lead medicinal chemistry efforts targeting GPCRs
• Independently manage CRO scientists in the design, development, and implementation of in vitro assays for the advancement of GPCR projects
• Execute weekly cell-based assays to screen/evaluate small molecule compounds in coordination with Biology, Chemistry, and Compound Management groups
• Interpret and analyze scientific data and work with cross functional teams to QC/communicate data in a timely manner
• Present experimental results/updates at team meetings
• Contribute to the management of the biology laboratory

Requirements

• Bachelor's or Master's degree in biochemistry, pharmacology, cell biology, or other related scientific areas, with a minimum of 3-5 years of industry experience (Sr. Associate Scientist I) or 6-8 years of industry experience (Sr. Associate Scientist II)
• Hands-on experience in cell biology and routine biological assays, including cell culture, HTRF and reporter gene cell-signaling assays, and imaging assays
• Demonstrated scientific rigor with proven ability to critically evaluate data, and think independently and creatively in developing and testing new scientific hypotheses
• Excellent oral and written communication skills
• Highly motivated to work in a cross-functional team setting
• Flexibility and ability to quickly learn new skills and knowledge on the job
• Hands-on experience with traditional and innovative screening methodologies for GPCRs, as well as concepts related to GPCR signaling and trafficking highly preferred
• Familiarity with HTS screening methodology is highly desirable
• Experience with design and implementation of in vivo models in coordination with CROs is highly desirable
• ABOUT IAMBIC THERAPEUTICS
• MISSION & CORE VALUES
• PAY AND BENEFITS

Benefits

Additional Information

JOB SUMMARY We are seeking a highly motivated and experienced Senior Associate Scientist I/II to join the GPCR Biology group and advance our core mission of accelerating small molecule drug discovery programs at Iambic Therapeutics. The successful candidate will have a proven track record of supporting in vitro cell-based assays to advance pre-clinical projects. The candidate will work closely with a cross-functional team that integrates machine learning, medicinal chemistry, analytical technology and biology to revolutionize small-molecule therapeutics design and discovery. This role is based at our San Diego headquarters.

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