Apprentice - In Vitro

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Be the First to Apply Division Piramal Pharma Solutions Piramal Pharma Solutions is a contract development and manufacturing organization (CDMO), offering end-to-end development and manufacturing solutions across the drug life cycle. We serve our clients through a globally integrated network of facilities in North America, Europe and Asia. This enables us to offer a comprehensive range of services including Drug Discovery Solutions, Process & Pharmaceutical Development services, Clinical Trial Supplies, Commercial supply of APIs and Finished dosage forms. We also offer specialized services like development and manufacture of Highly Potent APIs and Antibody Drug Conjugation. Our capability as an integrated service provider & experience with various technologies enables us to serve Innovator and Generic companies worldwide. For more details, please visit : www.piramalpharmasolutions.com Job Title Apprentice - In Vitro Job Description Bioanalytical method development and method validation of LC-MS/MS methods for Analyte and metabolites in biological matrixes.  Subject sample analysis according to SOP/Protocol.  Bioanalysis of Drug metabolism studies including metabolic stability, Hepatocyte stability, metabolite identification (Phase-I, Phase-II), CYP inhibition, Log P and Log D, Blood Stability, Plasma protein binding, bio relevant media Stability, Permeability Study CACO2, MDCK, MDR1, and Solubility studies in in Vitro systems using LC-MS/MS analysis.  Provide inputs towards chromatographic and mass spectrometric advancement and challenges.  Troubleshooting of LCMSMS instrument in case of any malfunction.  Interact and communicate professionally with Service engineer in case of malfunction of instrument and also Application scientist for NEW assay development.  Operation calibration and maintenance of all lab equipment (LCMSMS, Analytical balance, pH meter, micropipette, etc.). Bioanalytical method development and method validation of LC-MS/MS methods for Analyte and metabolites in biological matrixes.  Subject sample analysis according to SOP/Protocol.  Bioanalysis of Drug metabolism studies including metabolic stability, Hepatocyte stability, metabolite identification (Phase-I, Phase-II), CYP inhibition, Log P and Log D, Blood Stability, Plasma protein binding, bio relevant media Stability, Permeability Study CACO2, MDCK, MDR1, and Solubility studies in in Vitro systems using LC-MS/MS analysis.  Provide inputs towards chromatographic and mass spectrometric advancement and challenges.  Troubleshooting of LCMSMS instrument in case of any malfunction.  Interact and communicate professionally with Service engineer in case of malfunction of instrument and also Application scientist for NEW assay development.  Operation calibration and maintenance of all lab equipment (LCMSMS, Analytical balance, pH meter, micropipette, etc.). MSc-Biology

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