Senior Scientist II Medicinal Chemistry, Oncology

Responsibilities

• Conduct research in a large, multi-functional medicinal chemistry organization.
• As part of a project team, devise & execute synthetic routes to generate potential drug targets.
• Learn to use institutional software & tools to enable & accelerate design of new drug targets.
• Conceive & execute hypothesis-driven medicinal chemistry projects to optimize safety, ADME, & efficacy.
• Optimize routes to scale-up materials for key in vivo studies.
• Apply novel synthetic methodologies to access challenging targets.
• Analyze products using NMR, HPLC, LCMS, SFC, & other analytical tools to characterize reaction yields, product purity, & enantiomeric excess.
• Analyze & interpret in vitro & in vivo data from preclinical studies to inform design of next generation potential drug targets.
• Create scientific presentations & manuscripts for effective communication with internal stakeholders & international chemistry community.
• Education & Experience
• Must have a PhD in Organic Chemistry or other related scientific field & 2 years of academic or industry laboratory research experience.
• Of experience required, must have 2 years with each of the following:
• conceiving & executing synthetic organic chemistry projects with knowledge of contemporary synthetic techniques;
• characterizing organic compounds using NMR, HPLC, LCMS, & SFC, to quantify reaction yields, product purity, & enantiomeric excess;
• designing and executing multi-gram syntheses, multi-step synthesis campaigns, and reaction optimization;
• using electronic lab notebooks;
• acting as a lead scientist in an area of expertise on 1 or more projects; &
• training & mentoring junior scientists.
• Alternatively, would accept a MSc in Organic Chemistry or other related scientific field & 4 years of academic or industry laboratory research experience. Of experience required, must have 4 years with each of the following: (i), (ii), (iii), (iv), (v) & (vi).
• Experience may be gained concurrently. Would accept any suitable combination of training, education & work experience.
• Salary Range: $148,500.00- $202,500.00 per year
• Apply online at https://careers.abbvie.com/en or send resume to Job.opportunity.abbvie@abbvie.com . Refer to Req ID: REF49815W
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• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees. This job is eligible to participate in our short-term and long-term incentive programs.
• AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
• US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html
• US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:
• https://www.abbvie.com/join-us/reasonable-accommodations.html

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