Associate Scientist I, Immunology

Responsibilities

• Conduct original research supporting the RDC mission and Tonix portfolio of Immunotherapeutics against diverse disease conditions (e.g., autoimmunity, oncology)
• Support the development of robust and diverse in-vivo autoimmune models by conducting downstream ex vivo sample processing, analysis, and study results compilation
• Carry out under the direction of senior oversight efforts to develop novel methods and assays to contribute to the RDC research pipeline
• Plan and execute in-vitro and ex-vivo studies against study timepoints, project deadlines, and company goals
• Collect, analyze, and evaluate data
• Interpret data, make decisions, and conduct troubleshooting on related technical issues
• Prepare scientific presentations and reports for internal review and discussion
• This is a fast-paced challenging position offering competitive compensation and benefits package. This position will report to the Director of Immunology and will be based at the Tonix Research and Development Center in Frederick, Maryland.
• Essential Duties & Responsibilities
• Carry out tasks necessary to optimize and standardize in-vivo, ex-vivo and in-vitro autoimmune models to ensure consistent reliability and reproducibility of outcomes.
• Following training, independently process tissue samples for analysis by multi-parameter spectral flow cytometry, in-vivo imaging and contemporary molecular approaches.
• Using sterile techniques, maintain mammalian cell lines and perform cell culture tasks including primary cell isolation from both human- and lab animal-derived sources.
• Run ELISAs and other plate-based assays, analyze and interpret data with attention to quality and reproducibility, and be able to present results in team meetings.
• Independently troubleshoot, problem-solve, and execute directives and day-to-day tasks, while effectively incorporating feedback and adapting to evolving project needs.
• Work cross-functionally in a matrix environment, pa

Additional Information

Tonix Pharmaceuticals* is a fully integrated, commercial-stage biotechnology company focused on central nervous system (CNS) and immunology treatments in areas of high unmet medical need. TONMYA® (cyclobenzaprine HCl sublingual tablets 2.8 mg) is the first new treatment for fibromyalgia in adults in more than 15 years. Tonix's CNS commercial infrastructure supports its marketed products, including its acute migraine products, Zembrace® Symtouch® (sumatriptan injection 3 mg) and Tosymra® (sumatriptan nasal spray 10 mg). Tonix is investigating TONMYA® in Phase 2 clinical trials to evaluate its potential in major depressive disorder and acute stress disorder/acute stress reaction. Tonix is also advancing a pipeline of immunology programs, including TNX-4800, a Phase 2 ready long-acting human anti- Borrelia OspA monoclonal antibody (mAb) for the prevention of Lyme disease in the U.S., and TNX-1500, a Phase 2 ready third-generation CD40 ligand inhibitor for the prevention of kidney transplant rejection. In addition, the Company is progressing TNX-2900 (intranasal potentiated oxytocin), which is Phase 2 ready for the treatment of Prader-Willi syndrome, a rare disease. To learn more, visit www.tonixpharma.com and follow the Company on LinkedIn and X . *Tonix's product development candidates are investigational new drugs or biologics; their efficacy and safety have not been established and have not been approved for any indication. Zembrace SymTouch and Tosymra are registered trademarks of Tonix Medicines. TONMYA is a registered trademark of Tonix Pharma Limited. All other marks are property of their respective owners. Position Overview Tonix is seeking an Associate Scientist I to join a rapidly growing and dynamic discovery and development team. The successful candidate is expected to have a sufficient understanding of the biomedical sciences, ideally immunology. This is an excellent entry-level opportunity to directly participate and obtain exposure to a range of functional areas pertaining to the product development process including early-stage therapeutic discovery, nonclinical safety, pharmacological evaluation, and preclinical drug development. The duties will require the successful candidate to exercise some independent discretion and judgment while carrying out predetermined research and day-to-day tasks in BSL/2 and ABSL/2 environments. Experience working in a laboratory environment, performing day-to-day tasks independently, and working collaboratively in a team environment are required. The position is located at the Tonix Research and Development Center (RDC) which is the innovation and development arm of Tonix Pharmaceuticals. The RDC houses state-of-the-art equipment (e.g., high content imaging, mass spectrometry, spectral flow cytometry, in-vivo imaging, multi-parallel bioreactors, etc.) and is responsible for development of efficient and cutting-edge treatment methods for various diseases including infectious diseases, oncology, and other indications.

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