Research Associate - Engineered Antiviral Resilience

About the role

Company description: University of Sheffield Job description: We are seeking an enthusiastic, driven, and highly skilled Postdoctoral Research Associate who will thrive within our supportive culture of clinicians and scientists. This 4-year project led by Professor Thushan de Silva aims to develop a ground-breaking pan-viral prophylactic therapy by programming innate immunity within the nasal epithelium. This job is part of an Advanced Research + Invention Agency-funded project. You must hold a PhD in virology, immunology, or a related field, and possess extensive experience in both cell and viral culture. You are a dedicated team player with excellent communication skills and a desire to contribute to a world-leading research environment. As the successful candidate, you will work at the cutting edge of cell biology, virology, and single-cell genomics. You will be responsible for generating complex cellular models of the human upper respiratory tract using Air-Liquid Interface (ALI) cultures and conducting sophisticated viral infection studies. Your work will involve characterizing cellular states through single-cell multiomic assays, such as scRNA-seq and scATAC-seq, to identify and engineer target cell states that exhibit maximum antiviral efficacy. This role offers a unique opportunity to translate fundamental biological insights into potential therapeutics while collaborating closely with world-class partners in the USA and the Netherlands. The University of Sheffield is a remarkable place to work. Our people are at the heart of everything we do. Their diverse backgrounds, abilities and beliefs make Sheffield a world-class university. We offer a fantastic range of benefits including a highly competitive annual leave entitlement (with the ability to purchase more), a generous pensions scheme, flexible working opportunities, a commitment to your development and wellbeing, a wide range of retail discounts, and much more. Find out more at sheffield.ac.uk/jobs/benefits and join us to become part of something special. We build teams of people from different heritages and lifestyles from across the world, whose talent and contributions complement each other to greatest effect. We believe diversity in all its forms delivers greater impact through research, teaching and student experience.

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