Scientist II, Cheminformatics

About the role

Relay Therapeutics is seeking a highly motivated Scientist to join our Drug Discovery team in a unique hybrid role that integrates synthetic chemistry with cheminformatics. This position is ideal for a scientist who enjoys working at the interface of experimental and computational disciplines and is excited to help shape how data-driven chemistry is done in a modern biotech environment. Your Role: Maintain and support tools used in compound registration, lab operations and data ingestion from assays, as well as broader data and software access workflows Design and execute synthetic chemistry workflows, with a focus on high-throughput or parallel synthesis to support medicinal chemistry programs Contribute to the design, enumeration, and prioritization of compound libraries using cheminformatics tools Collaborate closely with computational chemists, data scientists, and medicinal chemists to guide compound design using data-driven insights Analyze and interpret experimental data to inform structure-activity relationships (SAR) and compound optimization Help develop and refine internal workflows that integrate synthetic chemistry with computational approaches Maintain clear documentation and communicate results effectively across multidisciplinary teams Your Background: Ph.D. or M.S. in Organic Chemistry or a related field, with 2-5 years of relevant industry experience preferred Demonstrated experience in synthetic organic chemistry Familiarity with cheminformatics tools and concepts (e.g., molecular representations, library design, property prediction) Experience with scripting or data analysis tools (e.g., Python, RDKit) Strong problem-solving skills and the ability to work both independently and collaboratively Excellent communication skills and a desire to work in a highly cross-functional environment

Requirements

• A scientist who enjoys bridging "hands-on" chemistry with computational thinking
• Someone comfortable working in a fast-paced, evolving biotech setting
• A candidate who is curious, adaptable, and interested in shaping new ways of integrating chemistry and data science
• Estimated Salary Range : [$88,000-$126,000].
• The range provided above is based on what we believe to be a reasonable estimate for this job at the time of posting. Actual base salary will depend on a number of factors, including but not limited to, a candidate's education, experience, skills and location.
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• About Relay Therapeutics

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