Senior Laboratory Research Scientist - Structural Biology

About the role

Short summary We are seeking a Senior Laboratory Research Scientist to join the Structural Biology STP and support innovative structural biology and biophysics projects across the Crick. You will play a key role in protein structure determination and molecular interaction studies, working closely with multidisciplinary teams to deliver high-quality structural and biophysical data. This is an exciting opportunity for an experienced scientist who enjoys hands-on laboratory work, technical problem-solving and collaborative research in a highly dynamic environment. Key Responsibilities These include but are not limited to: Establishing protein purification workflows for structural biology and biophysical studies. Determining protein structures using X-ray crystallography techniques. Performing biophysical characterisation of molecular interactions using techniques such as SPR, BLI, ITC and MST. Analysing and interpreting structural and biophysical datasets. Supporting training activities for researchers and platform users across the Crick. Contributing to method development and optimisation within the platform. Collaborating with interdisciplinary teams across a broad range of research areas. About you You will have: PhD in structural biology, biophysics or related discipline, or equivalent experience.* Strong experience in protein X-ray crystallography, including crystallisation, data collection and structure refinement.* Hands-on experience with biophysical interaction techniques such as SPR, ITC, BLI or MST.* Experience analysing quantitative biophysical data.* Excellent communication, organisational and collaborative working skills.* Proactive, adaptive and solutions-focused approach.* About us The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases. An independent organisation, its founding partners are the Medical Research Council, Cancer Research UK, Wellcome, UCL, Imperial College London and King's College London. The Crick was formed in 2015, and in 2016 it moved into a new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under one building in Europe. The Francis Crick Institute will be world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; developing emerging talent and exporting it to the rest of the UK; public engagement; and helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy. Please apply via the 'Apply' button above. From £47,080 with benefits, subject to skills & experience

Your Match

How well this role fits your profile.

Company Intel

What employees say

Worked at The Francis Crick Institute? Share your experience