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Research Associate - tRNA and mRNA Biology

External
Scismic logoScismic · Cambridge, MA
Full-timeOn-site12mo ago
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Requirements

  • A BS/MS in Neurobiology, Molecular/Cellular Biology, physiology, or a related discipline.
  • Extensive hands-on experience with a variety of molecular, cellular and/or physiological techniques (isolating rodent neurons and establishing primary neuronal cultures, neurite outgrowth, qPCR, western blotting, microscopy, calcium imaging, synaptic imaging, multi-electrode arrays, human IPS/ES cell culture, etc).
  • Prior experience using AAV/lentivirus in primary or iPSC-derived neurons is highly desirable.
  • Ability to master new concepts and technologies quickly and run experiments independently.
  • Scientifically rigorous, highly organized, with excellent oral and written communication skills.
  • Ability to work independently as well as collaborate with colleagues and effectively prioritize and manage multiple tasks in a fluid, fast-paced work environment

Additional Information

Scismic is supporting the growth of a Cambridge, MA biotech startup that is pioneering mRNA-modulating therapies to cure a broad range of genetic diseases. The company is exploring the use of its novel platforms in neurological disorders, heart disease, and muscular dystrophies. Position summary: As an expert scientist in cellular neurobiology, you will be responsible for establishing cellular assays to demonstrate in vitro proof of concept for company tRNA therapeutic leads and characterize the cellular activity and downstream disease-relevant biology to help prioritize candidates for in vivo studies. Title commensurate with level of experience. We are accepting applications to build a pipeline of potential candidates for future opportunities. If your qualifications align with our requirements, we will contact you once the hiring process begins. Thank you for your interest in this role.


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