Associate Principal Scientist (Associate Director), Health Economic and Decision Sciences

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Job Description We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we "follow the science", great medicines can make a significant impact to our world. And we believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe. We have an exciting opportunity for a new Associate Principal Scientist to join our Health Economic and Decision Sciences (HEDS) group. The Health Economics and Decision Sciences (HEDS) department is part of Our Company's Biostatistics and Research Decision Sciences (BARDS) organization. BARDS provides strategic design and analysis to support decision-making across Our Company's product discovery, development, and delivery, and applies quantitative scientific methods to advance drugs and vaccines for patients and global public health. In collaboration with internal and external partners, the BARDS-HEDS department specifically provides strategic and technical leadership to enable patient access, measure and quantify the value of Our Company's products, inform internal and external decisions, and shape methodology and external health policy and practice. The focus of this position is multi-folded covering several important areas that are important for HEDS priorities, modeling strategy and model adaptations. Under the guidance of the scientists in Regional HEDS, the incumbent will support the local markets for local adaptation of global Health Economics Models in Asia-Pacific (AP), Eastern Europe, Middle East, Africa (EEMEA), Latin America (LATAM) and Mid- Europe Region (MER) aligned with Value & Implementation strategies and Local Market Access priorities. A close collaboration with global/ regional teams and local markets including different functions, such as: Regional and Local Market Access leads, Regional Outcomes Research leads, Global Health Economics leads and Global Outcomes Research leads, is required to ensure consistency and alignment with strategies. In addition, the incumbent will support planning, delivery, communication and change management associated with a global multi-functional adoption of a specific platform for health economic modeling in oncology (e.g. THEOREM). Other technologies and integrations may fall in scope of this role in future. The new hire will also support Regional HEDS Executive Director with specific operational and strategic tasks that are important for the Regional and overall HEDS department. This job will require 15-20% of travel. Primary responsibilities: Specific to model adaptations (50%) Under the guidance of the Executive Director and Regional HEDS leads supporting all therapeutic areas in AP, EEMEA, LATAM and MER Shares with local markets the responsibility for health economic model adaptations for markets Works with local and regional Market Access/Outcomes Research/Value & Implementation to plan for health economic model adaptation needs in the region. Works with local, regional and HQ teams to align on market, product-specific health economic strategies model inputs Conducts or supervises the execution of health economic model adaptations. Ensures quality of health economic model adaptations. In markets that prefer to conduct model adaptation using a qualified local supplier or by internal Company staff: Ensures qualification of the local supplier and/or local Company staff, Ensures appropriate training of the health economic models and model adaptation guides Critically reviews model inputs, calculations and outputs of local health economic analysis to ensure quality. Assists local and regional Outcomes Research and market access colleagues answering any questions coming from the HTA bodies/decision makers. Coordinates and aligns with internal stakeholders to achieve consistent, high quality and timely model adaptations and submissions. Helps with guidance to consistently improve our Ways of Working to be more efficient in all the phases of health economic model adaptations. Specific to THEOREM (platform for health economic modeling in oncology) (25%) Under the guidance of Regional HEDS Executive Director and THEOREM Business System owner Provides input to THEOREM team on new feature requests. Helps complete User Acceptance Testing (UAT) for features introduced in THEOREM releases. Assists with THEOREM user questions that are specific to model calculations and logic functions. Helps THEOREM team triage and address incoming questions, new requests, feature requirements, and user support needs from HEDS. Specific to Strategic and Operational Tasks (25%) Under the guidance of Regional HEDS Executive Director Coordinates health economic modeling activities across 4 regions to ensure consistency and share learnings Helps with communication of HEDS Regional impact to senior management/other stakeholders through preparation of slide decks, newsletters etc Helps with

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