Sr Scientist I Pharmacology

Responsibilities

• Demonstrate scientific initiative and creativity in GPCR pharmacology research and development activities.
• Independently develop and validate cell-based and biochemical assays to characterize GPCRs.
• Apply advanced techniques to assess biased agonism, receptor internalization, trafficking, and signaling pathway modulation.
• Utilize high-throughput screening methods to identify novel GPCR modulators.
• Implement emerging technologies, such as biosensor assays and CRISPR-based gene editing, for assay development.
• Analyze and interpret complex data to draw conclusions and inform decision-making.
• Collaborate with cross-functional teams, including chemists, to support obesity research projects and SAR analyses.
• Maintain accurate and detailed records of experiments and results and adhere to corporate safety and compliance standards.
• Serve as primary author for scientific and regulatory reports and present findings to appropriate stakeholders.
• Bachelor's Degree or equivalent education and typically 10 years of experience, Master's Degree or equivalent education and typically 8 years of experience, PhD and no experience necessary.
• Degree in Pharmacology, Cell Biology, Biochemistry, or related discipline (preferred), with relevant post graduate experience.
• Familiarity with quantitative assay development, data analysis, and interpretation in drug discovery.
• Experience in obesity, metabolic, or related disease area research is strongly preferred.
• Demonstrated ability to think independently, troubleshoot, and lead projects.
• Experience with laboratory automation and high-throughput screening is a plus.
• Demonstrated ability to thrive in a fast-paced, cross-functional, and dynamic environment, function independently, communicate effectively, and collaborate closely with others.
• Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
• This job is eligible to participate in our short-term incentive programs.
• AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
• US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html
• US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:
• https://www.abbvie.com/join-us/reasonable-accommodations.html

Benefits

Additional Information

Purpose: Drive the discovery of innovative therapies and treatments for obesity by designing and executing creative experimental strategies grounded in molecular pharmacology, with emphasis on GPCR signaling, trafficking, and efficacy. Lead efforts to develop and optimize advanced in-vitro biochemical and cell-based assays to produce high-quality data with direct translational impact. Propel scientific innovation in GPCR pharmacology and obesity research by fostering robust, cross-functional collaborations, integrating multidisciplinary expertise, and leveraging technological advancements to accelerate drug discovery.

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