Senior Scientist, Molecular & Viral Safety

Responsibilities

• Perform DNA and RNA extraction from a variety of sample types (e.g., tissues, cell cultures, in-process samples) following standardized procedures.
• Prepare NGS libraries using automated and manual workflows for platforms such as Illumina and Oxford Nanopore Technologies.
• Operate, troubleshoot, and maintain laboratory instrumentation including sequencers, thermocyclers, and liquid handling robots.
• Perform quality control (QC) assessments using fluorometric quantification (e.g., Qubit), electrophoresis, and fragment analysis (e.g., TapeStation).
• Process raw sequencing data and perform routine bioinformatics tasks such as quality trimming, read mapping, basic variant calling, and generating summary metrics/reports using established pipelines.
• Execute and adapt basic command-line bioinformatics tools (e.g., FastQC, BWA/Minimap2, Samtools, bcftools) and utilize workflow managers or pipelines where applicable.
• Prepare, visualize, and interpret data outputs (e.g., coverage plots, QC summaries, variant tables) and communicate results to cross-functional teams.
• Work with bioinformatics colleagues to validate and implement new analysis pipelines and troubleshoot analysis issues.
• Utilize and be familiar with high-performance computing (HPC) environments, job schedulers (e.g., SLURM), and basic cluster file system concepts; transfer and manage sequencing data securely between local workstations and shared compute resources.
• Adhere to good laboratory practices (GMP), standard operating procedures (SOPs), safety policies, and quality assurance protocols to ensure accuracy, compliance, and reproducibility.
• Record, manage, and organize experimental data using electronic laboratory notebooks (ELNs) and other digital systems, ensuring data integrity and traceability of computational analyses.
• Support laboratory operations, including inventory management, ordering, and restocking of consumables and reagents.
• Contribute to technical reports, study summaries, and sections of regulatory filing documents, including documentation of computational methods and software versions.
• Participate in method optimization, implementation of new technologies, and continuous improvement of laboratory and computational workflows.
• Collaborate effectively with colleagues across functions (e.g., analytical development, process development, quality, manufacturing, bioinformatics) in a fast-paced, integrated, multidisciplinary team environment.
• Education Minimum Requirement
• Ph.D.; or
• Master's degree with a minimum of 5+ years of relevant experience; or
• Bachelor's degree with a minimum of 8+ years of relevant experience in virology, microbiology, molecular biology, biological sciences, or a related discipline, preferably in the biopharmaceutical industry.
• Required Experience and Skills
• Strong background and direct experience with core virology, molecular biology, and/or microbiology techniques (e.g., PCR/qPCR, nucleic acid extraction).
• Extensive experience with Next-Generation Sequencing workflows, including library preparation, run setup, and sequencing performance evaluation.
• Experience with automated liquid handling platforms or automated library preparation systems.
• Experience developing molecular methods and strong, systematic troubleshooting skills.
• Demonstrated ability to follow SOPs, generate high‑quality data, and maintain accurate laboratory documentation.
• Strong organizational and time‑management skills, with the ability to deliver on multiple priorities under strict timelines in a rapidly changing environment.
• Demonstrated ability to work effectively in a diverse, cross‑functional, team‑based environment.
• Demonstrated scientific contributions through publications in peer‑reviewed journals, conference presentations, or internal technical reports.
• Excellent verbal and written communication skills, demonstrated creativity, and strong interpersonal skills.
• Ability

Benefits

Additional Information

Job Description The Molecular & Viral Safety group within Cell-Based Sciences is seeking a detail-oriented, technically skilled Senior Scientist to support daily operations in our Next Generation Sequencing (NGS) laboratory and contribute to multidisciplinary analytics. This hands-on role is ideal for someone with a strong background in molecular biology techniques and an interest in basic bioinformatics and computational workflows. The successful candidate will be responsible for executing established protocols for nucleic acid extraction, library preparation, sequencing, and will perform routine data processing and basic bioinformatics analyses . The senior scientist will collaborate within a dynamic, integrated, and multidisciplinary team supporting both vaccine and biologics modalities and will contribute to the development and implementation of next‑generation sequencing technologies to help ensure that our products are free of adventitious agents as well as provide sequencing support to other priority programs of our Company.

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Company Intel

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