HEOR Science Liaison

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Company introduction: Compass Pathways plc (Nasdaq: CMPS) is a biotechnology company dedicated to accelerating patient access to evidence-based innovation in mental health. The Company is headquartered in London, UK, with offices in New York City in the US. We focus on developing novel treatments that have the potential to improve the lives of those who are suffering with mental health conditions and who are not helped by current treatments. We are pioneering a new paradigm for treating mental health conditions focused on rapid and durable responses through the development of our investigational COMP360 synthetic psilocybin treatment, potentially a first in class treatment. COMP360 has Breakthrough Therapy designation from the US Food and Drug Administration (FDA) and has received Innovative Licensing and Access Pathway (ILAP) designation in the UK for treatment-resistant depression (TRD) due to the pressing unmet need in this area. We are currently in phase 3 for TRD, have completed phase 2 studies for both post-traumatic stress disorder (PTSD) and anorexia nervosa and are planning a further late-stage study in PTSD. We envision a world where mental health means not just the absence of illness but the ability to thrive. - Compass Pathways . Job overview : The Field-Based Health Economics & Outcomes Research (HEOR) Science Liaison is a scientifically trained, field-based expert, serving as a scientific bridge to external healthcare decision makers (HCDMs), including MCOs, PBMs, IDNs, ACOs, SPPs, and HTA bodies. The HEOR Science Liaison delivers credible, non-promotional scientific exchange across clinical evidence, real-world evidence (RWE), pharmacoeconomics, and health outcomes to support informed formulary, coverage, and reimbursement decisions. The role spans the full product lifecycle and is key to demonstrating the value of innovative therapies to payer and access stakeholders. Location: Remote in the United States. Reports to: Director, HEOR. Roles and responsibilities ( Include but are not limited to ): External Scientific Engagement Identify, cultivate, and maintain peer-to-peer relationships with key payer thought leaders, formulary decision makers, Chief Medical Officers, Chief Pharmacy Officers, and other HCDMs within assigned geography Deliver fair-balanced, scientifically rigorous presentations on clinical data, real-world evidence, pharmacoeconomic models, budget impact analyses, and patient-reported outcomes (PROs) Respond to unsolicited medical information requests from payer and access stakeholders with accurate, compliant, and timely scientific content Attend and represent the organization at managed care, payer, and scientific conferences to maintain awareness of current landscape issues and emerging data HEOR Evidence Generation & Dissemination Partner with internal HEOR, RWE, and Medical Affairs teams to identify evidence gaps and support the design, execution, and dissemination of field-based observational studies, retrospective analyses, and pharmacoeconomic research Facilitate investigator-initiated and collaborator-initiated research proposals; coordinate with appropriate internal stakeholders for review and approval Support development and communication of health economic models, cost-effectiveness analyses, and budget impact tools for payer audiences Contribute to publications, posters, and abstracts for scientific meetings and peer-reviewed journals Payer Landscape Intelligence & Insights Gather and synthesize field intelligence on evolving payer policies, formulary decisions, coverage criteria, value-based contracting trends, and competitive landscape dynamics Communicate insights to internal stakeholders including Medical Affairs, Market Access, HEOR, and Commercial teams to inform strategy and evidence planning Monitor and interpret changes in managed care regulations, government payer policy (CMS, Medicare, Medicaid, VA/DoD), and HTA methodologies Cross-Functional Collaboration & Training Serve as a scientific resource to Market Access Account Directors, Commercial teams, and other field-based colleagues; provide training on disease state, clinical data, and health economics topics Collaborate with Medical Science Liaisons (MSLs), Global Medical Affairs, and HEOR headquarters teams to align field activities with overarching medical strategy Appropriately collaborate with the Market Access team to educate and inform payers about clinical and health economic aspects of Compass Pathways' investigational and on-market products Participate in advisory board activities, scientific symposia, and payer-focused medical education programs Complete all required training, compliance reporting, and administrative responsibilities in accordance with corporate policy and applicable law Candidate Profile: Advanced degree required, M.D., D.O., Pharm.D., or Ph.D. preferred, in a relevant scientific or health-related discipline (health economics, pharmacoeconomic

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