Director, Translational Immunology

Responsibilities

• Program Leadership and Scientific Strategy
• Serve as the immunology lead supporting a late-stage clinical development program.
• Contribute to the development and execution of nonclinical and translational strategies aligned with program team objectives.
• Partner with cross-functional teams to support program governance, development planning, and scientific decision-making.
• Assess emerging scientific, clinical, and competitive developments relevant to assigned program and associated strategy.
• Contribute to the identification and evaluation of new therapeutic opportunities in rare disease for the assigned program that may provide clinical benefit.
• Translational Science and Biomarkers
• Develop translational strategies linking mechanism of action, target engagement, pharmacodynamic activity, and clinical outcomes.
• Support identification and implementation of mechanistic, pharmacodynamic, predictive, and response biomarkers.
• Collaborate with cross-functional teams to support implementation of biomarker strategies and data interpretation throughout development.
• Contribute to scientific publications, presentations, and external communications.
• Nonclinical Development and Regulatory Support
• Collaborate with Regulatory and nonclinical colleagues to support regulatory submissions and health authority interactions.
• Interpret pharmacology, toxicology, and translational data in the context of clinical development and regulatory objectives.
• Support preparation and review of investigator brochures, briefing documents, regulatory submissions, and other development-related documents.
• Ensure research and translational activities are aligned with development plans and regulatory expectations.
• External Scientific Leadership
• Lead scientific interactions with CROs, academic collaborators, consultants, and key opinion leaders.
• Design, oversee, and contribute to interpretation of externally conducted translational and mechanistic nonclinical studies.
• Represent Travere at scientific meetings, conferences, and external collaborations.
• Identify and build productive scientific relationships that advance understanding of disease biology and therapeutic mechanisms.
• Organizational Leadership
• Contribute to building immunology and translational science capabilities within the Research and Nonclinical Development organization.
• Mentor colleagues and provide scientific leadership across programs and functions.
• Foster a culture of scientific excellence

Benefits

Additional Information

Department: 106200 Research & Non-Clinical Dev Location: San Diego, USA- Remote Be a part of a global team that is inspired to make a difference in the lives of people living with rare disease. At Travere Therapeutics, we recognize that our exceptional employees are vital to our success. We are a dedicated team focused on meeting the unique needs of rare patients. Our work is rewarding - both professionally and personally - because we are making a difference. We are passionate about what we do. We are seeking talented individuals who will thrive in our collaborative, diverse, fast-paced environment and share in our mission - to identify, develop and deliver life-changing therapies to people living with rare disease. We stick by our values centered on patients, courage, community, and collaboration to pursue our vision of becoming a leading biopharmaceutical company dedicated to the delivery of innovation and hope to patients in the global rare disease community. At Travere Therapeutics, we are in rare for life. We continue to courageously forge new paths as we move toward a common goal of elevating science and service for rare patients . Position Summary: Travere Therapeutics is seeking an experienced and strategic scientist to join our Research and Nonclinical Development organization as Director, Translational Immunology. This individual will serve as a key scientific leader supporting an assigned development program primarily for rare-kidney disease and will play an important role in advancing translational and nonclinical strategies across current and future indications. The successful candidate will bring deep expertise in immunology and immune-mediated disease, including a strong understanding of B-cell biology combined with experience supporting clinical-stage drug development programs. Knowledge of kidney disease would be an advantage. This individual will work closely with Clinical Development, Clinical Pharmacology, Biometrics, Regulatory, Medical Affairs, and external collaborators to develop translational strategies, support nonclinical development activities, evaluate emerging scientific opportunities, and help identify additional indications where the asset may also provide meaningful therapeutic benefit. This role also represents an opportunity to contribute to the growth of immunology capabilities within a dynamic Research and Nonclinical Development organization and to assume increasing scientific leadership responsibilities as the organization expands.

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