Director, Market Access Deal Analytics

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Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain's biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X . About This Role Axsome Therapeutics is seeking a Director, Market Access Deal Analytics to serve as a strategic leader in developing data-driven solutions that inform payer strategy, reimbursement optimization, pricing, and patient access. The ideal candidate will bring deep experience in payor and PBM deal analytics, strong understanding of payor incentives, Medicare and Medicaid reimbursement, understanding of specialty pharmacy, hub, patient services programs, and a pragmatic, action-oriented mindset that connects insights to execution. This position reports to the Senior Director, Pricing and Contracting Strategy. This role is based at Axsome's HQ in New York City with an on-site requirement of at least three days per week . We are unable to consider candidates who are looking for fully remote roles. Job Responsibilities and Duties include, but are not limited to, the following: Conduct robust analytics to support business cases to be presented to Pricing Terms Committee (PTC) Support development on contracting language that supports meeting of business intent Lead analytics strategy to inform payer contracting, coverage optimization, and payer engagement across Axsome's in-line and pipeline products Conduct claims data analyses [rejections, reversals, abandonment] to understand coverage dynamics, formulary behavior, and their implications on uptake and persistency Design modeling frameworks to guide formulary negotiations, segmentation strategies, and gross-to-net (GTN) investment optimization Build predictive tools to estimate how payer policies and pricing dynamics influence new therapy adoption across CNS specialties Drive integration of payer analytics into National Account pull-through strategy, including actionable field-level insights for Market Access and Field Sales teams Support development of key metrics, and report payer and PBM contract performance to Pricing Committee and Executive Leadership Construct scenario-based forecasting models that simulate the impact of price and access changes on revenue and patient access Monitor formulary positions and their downstream impact on prescribing behavior, conversions, and persistency to inform contract renewal cycles Partner with Finance and GTN teams to continuously refine accruals based on evolving pricing and access dynamics Collaborate closely with Forecasting, Commercial Operations, HEOR, and Market Access Data Science teams to harmonize analytics across functions Embed analytics into pricing and access strategy development, ensuring that all recommendations are grounded in data and aligned to business goals Proactively identify opportunities to improve data infrastructure, automate insight generation, and enhance decision support capabilities Requirements / Qualifications Bachelor's degree in Economics, Statistics, Public Health, or related field. Advanced degree (MBA, MPH, PhD) preferred Minimum 10 years in pharmaceutical or healthcare analytics with a focus on market access, pricing, or payer strategy Proven track record in supporting product launches from an access analytics perspective Strong background in CNS therapeutic areas or other specialty/rare disease domains, highly preferred Ability to work on site Monday, Tuesday & Thursday Experience, Knowledge and Skills In-depth understanding of U.S. payer systems (commercial, Medicare, Medicaid), reimbursement pathways, and formulary dynamics Proficiency in large-scale healthcare datasets (claims, syndicated data sources, longitudinal data sources) Strong experience in payer contracting analytics, GTN modeling, and assessing ROI on market access investments Expertise in PBM/Payor Contract Language Familiarity with data visualization platforms (e.g., Power BI, Tableau) and cloud-based data ecosystems Ability to develop and validate predictive models using machine learning or regression-based techniques Ability to influence senior stakeholders across Commercial, Access, and Corporate functions Experience managing external vendors, data par

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