Software Engineer, Web Application

Responsibilities

• Build and evolve a Python web application - its interface, the API layer behind it, and the supporting workflows.
• Work across the stack: server-rendered UIs (HTMX), FastAPI route handlers, and the underlying service layer.
• Work with domain experts (primarily chemists and biologists working on drug discovery projects) to understand requirements.
• Design interfaces that are usable and legible for non-engineers; contribute to onboarding materials and in-product guidance.
• Keep the web/HTTP layer a thin contract over the service layer - no business logic in route handlers - so the same logic is reusable by future entry points.
• Treat sensitive data with care: enforce authorization and access scoping on every request, and surface clear, safe error states rather than silent failures.
• Participate in design discussions, code reviews, and documentation.

Requirements

• Strong full-stack engineering skills with production Python, including building server-rendered UIs (e.g. HTMX).
• Experience building and operating production web applications or SaaS-style products.
• Comfort with HTTP API design and well-structured backend services (FastAPI or similar).
• Experience with relational databases.
• A track record of building usable interfaces for real users and iterating on feedback.
• Comfortable working closely with scientific or domain users on data-intensive problems.
• Awareness of web security fundamentals (authn/authz, session handling, handling sensitive data) preferred
• Familiarity with containerization and CI/CD preferred.
• Strong written communication and the ability to work effectively in a distributed team.
• TECH STACK & ENVIROMENT
• Python with modern tooling (e.g. uv, pixi)
• FastAPI with a clean service-layer architecture
• Server-rendered UIs (HTMX)
• PostgreSQL and object storage (S3)
• AWS (ECS and related services)
• Infrastructure-as-code and automated CI/CD; containerized services
• Agentic coding tools (e.g. Claude Code) as part of day-to-day development
• ABOUT IAMBIC THERAPEUTICS
• MISSION & CORE VALUES

Additional Information

JOB SUMMARY Iambic is building a secure, cloud-based platform for running our ML-driven drug-discovery workflows. You'll own and evolve our web application - the primary surface through which scientists interact with our drug-discovery platform. You'll work across the full stack, from the interface through the FastAPI HTTP layer down to the service layer, building features that are usable by non-engineers (chemists, biologists) and trustworthy with sensitive scientific data. This role suits an engineer who enjoys shipping end-to-end features on a product surface, cares about UX for a technical-but-non-developer audience, and is comfortable that the web layer is a thin, secure adapter over a shared service layer rather than a place for business logic. This position is based out of our new Ireland office.

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