Sr. Director, Advanced Technologies

About the role

We are looking for a dynamic and experienced Senior Director of Advanced Technologies to lead a team in scoping, evaluating, and implementing cutting-edge advancements in sequencing, sample preparation and new assay creation. This role will drive innovation in our proprietary technologies, enhancing performance and expanding capabilities. Your contributions will play a key role in shaping the next generation of genomics-based precision medicine products, supporting immuno-oncology, cancer clinical trials, diagnostics, and therapeutics used by pharma, biotech, hospitals, and clinicians.

Responsibilities

• Develop and execute the advanced technology strategy, ensuring alignment with company objectives and long-term vision.
• Lead efforts to evaluate and integrate new technologies that expand and improve Personalis products.
• Participate in forward-looking strategic planning and influence company-wide technology adoption.
• Identify new initiatives and build consensus across various stakeholder groups with clear success measures.
• Work closely with bioinformatics teams to design experiments and validate new procedures and analytics.
• Partner with the operations teams to ensure the smooth adoption of new technologies.
• Collaborate across functions to troubleshoot issues and implement solutions that drive efficiency.
• Influence company policy and strategy by partnering executive leadership.
• Recruit, mentor, and manage a high-performing team of scientists to drive innovation and operational excellence.
• Foster a culture of continuous learning, inclusion, and professional growth for all team members.
• Ensure accountability for results and provide strategic focus to support both short- and long-term organizational success.
• Demonstrate strong leadership, communication, and influence across all levels of the organization.
• Model and promote Personalis values, fostering collaboration and valuing diversity.
• Drive continuous innovation by encouraging the team to identify process efficiencies and new solutions.
• Support compliance with all department and company policies, ensuring regulatory and quality adherence.
• Work cooperatively across functions to achieve broader company objectives and business success.
• Education & Experience :
• Ph.D in a related field with 10+ years of relevant experience, preferably in molecular biology.
• Minimum of 5 years of management experience, with a proven ability to set a clear vision, establish expectations, and motivate teams to achieve results.
• Demonstrated success in driving performance, achieving objectives, and leading teams to meet departmental goals.
• Strong communication, presentation, and influencing skills, with the ability to effectively engage and gain support from senior leadership.
• Expertise in strategic thinking, decision-making, and negotiation, ensuring smooth daily business operations.

Benefits

Additional Information

Personalis is a genome-scale diagnostics company with a mission to pioneer genome guided medicine. Our priority is to obtain the most accurate genetic data from each sample, and then to draw the most reliable medically-focused conclusions from these. Our tests are based on whole human genome and exome sequencing, conducted in our state-of-the art laboratory. We analyze results utilizing proprietary databases, advanced human reference sequences, and sophisticated algorithms. Personalis is based in Fremont, California.

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