Research Officer - Neuroscience
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About the role
As a Research Officer, Neuroscience, you will support the design, coordination, and execution of laboratory-based experiments across two major neurodegeneration projects. Key responsibilities include: Processing and analysing human postmortem brain tissue from longitudinally characterised donor cohorts, Performing histological and molecular assays, including multiplex immunolabelling, staining, and microscopy-based imaging, Conducting alpha-synuclein seed amplification assays and proximity ligation assays for protein interaction studies, Supporting transcriptomic workflows, including sample preparation and coordination with sequencing platforms, Acquiring, managing, and organising experimental data, including high-resolution imaging datasets, Assisting with quantitative image analysis and interpretation of cell- and organelle-specific changes, Contributing to studies examining early nuclear and organelle dysfunction in frontotemporal dementia and Lewy body dementias, Supporting research into Parkinson's disease heterogeneity as part of a global initiative examining biological subtypes, Maintaining laboratory equipment, supplies, and consumables while ensuring compliance with biosafety, human tissue handling, and ethical guidelines, Contributing to the preparation of research outputs including reports, presentations, and manuscripts, Participating in group meetings and collaborative discussions with internal and external partners. The Faculty of Medicine, Health and Human Sciences (FMHHS) is ambitiously pushing the boundaries of progressive thinking and challenging what's possible to solve some of the big issues of our time, both nationally and on a global scale. The faculty forms part of M acquarie University Health, an integrated academic health sciences enterprise which incorporates Macquarie University Hospital and primary and speciality clinics. We have active research programs in biomedical and clinical sciences , cognitive and brain sciences, health systems, linguistics, physiotherapy, psychology and public health, amongst others. Our faculty hosts the Australian Institute of Health Innovation ( AIHI), an internationally acclaimed powerhouse researching health systems, e- health and patient safety. In learning and teaching, the faculty offers a unique suite of undergraduate and postgraduate courses in many areas, including clinical, health and human sciences, linguistics, medicine, psychology, physiotherapy, speech pathology and audiology. About You You are a motivated and detail-oriented researcher with strong laboratory skills and a genuine interest in understanding the mechanisms of neurodegenerative disease. You thrive in collaborative, multidisciplinary environments and bring both technical rigour and scientific curiosity to your work. Essential Selection Criteria: A relevant tertiary qualification in neuroscience, biomedical science, molecular biology, or a related discipline, Extensive experience in laboratory-based biomedical research, Extensive experience with histology, immunohistochemistry, or fluorescence imaging techniques, Skills in image analysis software or bioinformatics approaches, Demonstrated ability to analyse and interpret experimental results, Strong organisational skills and attention to detail in data recording and experimental procedures, and Ability to work both independently and collaboratively with