Staff Security Engineer, Detection and Response

About the role

Here at Ambience, we never set out to be just another scribe. We're building the AI intelligence platform that restores humanity to healthcare and drives meaningful ROI for health systems across the country. Our technology helps providers focus on delivering great care by removing the administrative burden that pulls them away from patients and away from their most impactful work. Ambience delivers real-time coding-aware documentation and clinical workflow support across ambulatory, emergency and inpatient settings at the top health systems in North America. Our teams operate relentlessly with extreme ownership to build the best solutions for our health system partners. We value candor, positivity and deep thought - and we expect a lot from each other because we know the problems we're solving truly matter. Ambience was ranked #1 for Improving the Clinician Experience in the KLAS Research Emerging Solutions Top 20 Report, recognized by Fast Company as one of the Next Big Things in Tech, named one of the best AI companies in healthcare by Inc., and selected as a LinkedIn Top Startup in 2024 and 2025. We're backed by Oak HC/FT, Andreessen Horowitz (a16z), OpenAI Startup Fund, and Kleiner Perkins - and we're just getting started. Ambience deploys clinical AI agents that operate in real time across the nation's largest health systems. When your product has autonomous access to infrastructure, credentials, and patient data at scale, detection and response isn't a support function, it's core to our business. You'll be our first dedicated D&R hire. You'll build the detection engineering and incident response program from scratch in a HIPAA-regulated, AI-native environment where the threat surface includes LLM-powered agents operating across infrastructure. You'll write production code, architect security data pipelines, and define what good looks like for D&R at a company where the attack surface is genuinely novel and rapidly evolving. Our engineering roles are hybrid in our SF office (3x/week).