Executive Director, DMPK

About the role

At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs. What We Do: Neurocrine Biosciences is a leading neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, neuroendocrine and neuropsychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, endometriosis* and uterine fibroids,* as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders because you deserve brave science. For more information, visit neurocrine.com , and follow the company on LinkedIn , X and Facebook . ( *in collaboration with AbbVie ) Develops strategic plans, objectives and policies for overall function. Leads the Preclinical Pharmacokinetics function within the Preclinical Development organization. Provides scientific leadership and oversight to ensure that clinical candidates with acceptable drug development characteristics are identified and appropriately characterized and developed. Plays a key role in the discovery and advancement of Neurocrine's development compounds. Works with Neurocrine colleagues to participate in all stages of Preclinical Pharmacokinetic assessments, from compound screening through to IND and NDA regulatory submissions. Represents Preclinical Development on Research and Development teams and regularly interfaces with internal and external colleagues to ensure timely and accurate dissemination of Preclinical Pharmacokinetics. _ Your Contributions (include, but are not limited to): Your Contributions (include, but not limited to): Provides strategic, functional leadership and oversight to the Preclinical Pharmacokinetic function within Preclinical Development Responsible for the development and enablement of departmental strategies to evaluate Preclinical Pharmacokinetics including ensuring continued expansion and/or updating of training, techniques and/or equipment Leads and manages the conduct, interpretation and reporting of preclinical pharmacokinetic studies Works with Research and Preclinical Development colleagues to establish optimal lead candidate characteristics, develop appropriate testing schemes, and design, conduct and report on preclinical studies intended to characterize potential drug candidates Designs & conducts Preclinical Pharmacokinetic and Toxicokinetic/Pharmacokinetic/Pharmacodynamic studies in support of clinical development compounds Oversees the preparation of Preclinical Pharmacokinetic sections of regulatory documents (IND, NDA, briefing books, Investigator Brochures, etc.). Actively leads/participates in research-stage and development-stage program teams from both a strategic and tactical level Prepares data summaries and presents results to peers, colleagues, the Management Committee and regulatory agencies Prepares Standard Operating Procedures (SOPs) as needed to guide the Preclinical Pharmacokinetics activities Performs other duties as assigned