Summer Student- Segal Lab

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The Segal Lab is focused on understanding mechanisms of chronic pain signaling by Dorsal Root Ganglia (DRG) sensory neurons. Specifically, our work aims to identify how the hormone and neurotransmitter, serotonin, modulates chronic pain in peripheral nerves. We are currently seeking a highly motivated Co-Op student to assist in a new lab initiative, investigating whether loss of the serotonin receptor, 5-HTR3A, in DRG neurons alters chronic pain behavior in mice experiencing neuropathy. This project will involve complex animal behavior analysis using genetic mouse models, along with computational data analysis, and basic molecular biology techniques. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. Will be trained and assist postdoctoral fellow Dr. Franco in carrying-out: - Mice- genotyping Htr3a mice - Intraperitoneal (IP) injections of drug compounds in mice - Computational data analysis and downstream statistical analyses - Mouse genotyping strategies (including PCR, gel electrophoresis) - Maintain a lab notebook detailing experimental protocols used, as well as shared databases containing raw data and analyses. - Participate in weekly lab meetings, and weekly one-on-one meetings with Drs. Segal and Franco. -Contribute to writing of abstracts based on work At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are committed to having faculty and staff who offer multifaceted experiences. Cancer knows no boundaries and when it comes to hiring the most dedicated and compassionate professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply. Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law. EEO Poster . Pay Transparency Statement The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate's relevant experience, skills and qualifications. For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA). $31,200.00 - $41,200.00

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