Lead pharmacovigilance activities and risk mitigation strategies for assigned oncology assets and clinical trials
Drive the evaluation and interpretation of safety data, including signal detection and assessment
Develop strategic approaches for safety issue evaluation within clinical development programmes
Contribute to safety components of global regulatory submissions (e.g., INDs, DSURs, IBs)
Perform literature review, clinical data synthesis, and integrated safety analyses to inform decision-making
Ensure high-quality, timely delivery while managing multiple priorities
Cross-Functional Matrix Leadership
Represent Safety Evaluation & Risk Management (SERM) on Clinical Matrix and Project Teams
Lead cross-functional efforts to address urgent and complex product safety issues
Partner closely with Safety Physicians and stakeholders to prepare for and contribute to Safety Review Team (SRT) meetings
Escalate emerging safety issues to senior leadership and governance bodies as appropriate
Build strong working relationships and lead effectively within a global matrix organisation
Coach and mentor colleagues as appropriate
Communication, Influence and Strategy
Present safety recommendations and emerging risks to senior governance committees
Represent GSK in interactions with regulatory authorities, external experts, and partners
Apply strategic thinking to evaluate internal and external factors influencing safety decisions
Contribute to the development of long-term safety and clinical programme strategies
Identify opportunities for continuous improvement and innovation in safety evaluation processes
Communicate complex scientific information clearly to a range of audiences
Why You?
Basic Qualification
We are seeking professionals with the following required skills and qualifications to help us achieve our goals:
Degree in a health-related discipline (e.g., Life Sciences, Pharmacy, Medicine, Nursing), with significant relevant experience
Substantial experience in pharmacovigilance, drug safety, or a related function within the pharmaceutical or biotechnology industry
Experience supporting safety in oncology clinical development programmes
Strong expertise in: Signal detection and risk assessment
Clinical trial safety oversight
Regulatory safety documentation and submissions
Knowledge of global pharmacovigilance regulations (e.g., ICH, GVP, CIOMS)
Proven ability to work effectively in a complex, global matrix environment
Strong analytical, communication, and problem-solving skills
Preferred Qualification
If you have the following characteristics, it would be a plus:
Advanced degree (e.g., PhD, PharmD, MD or equivalent)
Experience interacting with global regulatory authorities
Experience presenting to senior governance or safety review committees
Demonstrated leadership experience, including mentoring or team leadership in a matrix setting
Track record of influencing cross-functional teams and contributing to strategic decision-making
Experience supporting late-stage clinical development programmes
Working arrangement
This is a hybrid role based in the United Kingdom with a mix of office and remote working. Some travel may be required for meetings and regulatory interactions.
What we value
We seek people who work with integrity, focus on patients and collaborate respectfully. We welcome different perspectives and promote inclusion in our teams. We support development and learning so you can grow while making a meaningful impact on patient safety.
Apply now
If you are ready to use your scientific expertise to protect patients and shape global safety strategy, we would like to hear from you. Please submit your CV and a short cover letter expl
Benefits
Health insuranceRemote work options
Additional Information
Business Introduction
At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting-edge technology to transform people's lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients' needs and have the highest probability of success. We're uniting science, technology, and talent to get ahead of disease together.
Find out more:
Our approach to R&D
Position Summary
Provides advanced scientific expertise in the safety evaluation and risk management of key GSK oncology assets in clinical development. Leads the identification, assessment, and communication of safety risks to ensure robust benefit-risk profiles and protection of patients globally.
This role plays a critical part in shaping the safety strategy of innovative oncology therapies, partnering cross-functionally to enable high-quality, timely decision-making and proactive risk mitigation across the portfolio.
Gsk · – London – New Oxford Street, UK