Wibr · Cambridge, MAPrepare for this interview
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Classification: Exempt Job Family: Core Facilities Reports to: Director Genome Technology Core Job Description Summary: OVERALL RESPONSIBILITY The Genomics Technology Core Technician serves as a central point of expertise for sequencing and analytical operations. This role bridges wet-lab execution and computational analysis, supporting both short- and long-read sequencing workflows. The Technician will help internal and external clients on sequencing technologies, guide project design, manage client communication, and deliver rigorous data pre-processing, quality control, and downstream analysis. Will contribute to hands-on support in the laboratory as needed. CHARACTERISTIC DUTIES Advise clients on appropriate sequencing technologies (short-read, long-read, single-cell, spatial) and help define project parameters, expected outputs, and deliverables. Perform primary NGS data processing including demultiplexing, alignment, and quality assessment (FastQC, MultiQC, etc.). Conduct secondary analysis as required, including variant calling, differential expression, or genome assembly depending on project needs. Develop and maintain reproducible analysis pipelines. Use and update LIMS and genomics databases to track samples, datasets, and project metadata. Communicate effectively with researchers at all levels to ensure deliverables meet scientific objectives. Document protocols, analysis workflows, and results clearly for both technical and non-technical audiences. Assist with NGS related services, quality control (Bioanalyzer, TapeStation, Qubit), and sequencer operation as needed. Contribute to continuous improvement of core facility processes and standard operating procedures. Other tasks, as required.
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