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Director, Head of Product Management - AI-Enabled Precision Medicine (Therapeutics & Innovations)

External
natera logoNatera · Remote
Full-timeRemote3w ago
ForecastingLeadershipMachine Learning
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About the role

We are redefining the future of precision medicine by integrating AI with healthcare to create next-generation, precision treatment modalities. Our multidisciplinary team is building products at the intersection of clinical data, multi-omics, and machine learning-unlocking entirely new approaches to drug development and patient care. Within the Therapeutics & Innovations Business Unit, we are developing a new category that bridges diagnostics and therapeutics. Our platform combines deep scientific expertise with proprietary datasets to power AI-enabled solutions that can transform how therapies are discovered, developed, and deployed. We are looking for a product leader who can translate this potential into real, scalable products-owning the strategy, roadmap, and execution to bring these innovations to market. We are seeking a Director / Head of Product Management to lead product strategy and execution for our AI-enabled therapeutics platform. This is a highly cross-functional leadership role at the center of science, engineering, clinical development, and commercial strategy. You will define what we build, why it matters, and how it creates value-for biopharma partners, clinicians, and ultimately patients. You will own the product lifecycle end-to-end: from concept and validation through development, launch, and iteration. This role requires a rare blend of scientific fluency, product rigor, and commercial instinct . You will work closely with R&D, AI, medical, business development, and marketing to ensure our products are scientifically credible, operationally feasible, and commercially compelling.

Responsibilities

  • Product Strategy & Vision
  • Define and own the product vision and roadmap for AI-enabled tools for precision medicine offerings (e.g., biomarkers, trial enablement tools, co-development platforms) via genomic language models, biomedical AI agents, AI-driven analysis platforms, forecasting algorithms.
  • Identify high-value use cases across drug development (e.g., trial design, patient selection, translational insights, companion diagnostics).
  • Translate platform capabilities into clear product strategies aligned with business goals.
  • Product Development & Execution
  • Lead the end-to-end product lifecycle: concept → validation → build → launch → iteration.
  • Partner with R&D, data science, and engineering to define product requirements and ensure high-quality execution.
  • Drive prioritization decisions across competing opportunities based on impact, feasibility, and strategic alignment.
  • Customer & Market Insight
  • Engage with biopharma partners, clinicians, and internal stakeholders to deeply understand needs and workflows.
  • Synthesize customer insights into product requirements and roadmap decisions.
  • Continuously assess market trends, competitive landscape, and emerging technologies.
  • Cross-Functional Leadership
  • Serve as the central hub across Product, R&D, Clinical, BD, and Marketing.
  • Align stakeholders around a unified product strategy and execution plan.
  • Drive decision-making in a matrixed, fast-moving environment.
  • Commercialization & Launch
  • Partner with commercial and BD teams to define product positioning, packaging, and pricing.
  • Support go-to-market strategy, including pilot programs, partnerships, and scaled deployments.
  • Ensure successful product launches with clear value propositions and supporting evidence.
  • Data, Evidence & Validation
  • Define requirements for product validation, including analytical, clinical, and real-world evidence.
  • Ensure products meet scientific, regulatory, and commercial expectations.
  • Partner with clinical and regulatory teams to align product strategy with approval pathways where applicable.
  • Team Building & Leadership
  • Build and mentor a high-performing product management function.
  • Establish product processes, operating cadence, and best practices.
  • Foster a culture of ownership, speed, and scientific rigor.

Requirements

  • Advanced degree (PhD, MD, MS, or equivalent) in life sciences, bioengineering, computational biology, or related field preferred.
  • 8-12+ years of experience in product management, product strategy, or related roles in biotech, life sciences, or healthcare technology.
  • Proven track record of building and launching complex, data-driven products.
  • Strong understanding of drug development workflows and/or clinical diagnostics.
  • Experience working with AI/ML-driven products or data platforms is highly preferred.
  • Exceptional ability to translate complex science into clear product decisions and strategies.
  • Demonstrated success leading cross-functional teams in ambiguous environments.
  • Strong commercial acumen, including product-market fit, pricing, and partnership models.
  • Bonus:
  • Experience with biomarker development, oncology, or precision medicine.
  • Background in diagnostics + therapeutics integration.
  • Ex

Benefits

Health insuranceVision insurancePerformance bonus

Additional Information

Director, Head of Product Management - AI-Enabled Precision Medicine (Therapeutics & Innovations)


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