Manager/Senior Manager, Clinical Site Payment Reconciliation and Optimisation

About the role

BeOne is a global oncology company that is discovering and developing innovative treatments that are more affordable and accessible to cancer patients worldwide. With a broad portfolio, we are expediting development of our diverse pipeline of novel therapeutics through our internal capabilities and collaborations. We are committed to radically improving access to medicines for far more patients who need them. Our growing global team of more than 10,000 colleagues spans five continents, with administrative offices in Basel, Beijing, and Cambridge, U.S. To learn more about BeOne , please visit www.beonemedicines.com and follow us on LinkedIn and X (formerly known as Twitter). BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer. Job Description: General Description: The Manager/Senior Manager, Site Payment Reconciliation & Optimisation is a strategic and operational leader within Clinical Business Operations (CBO), responsible for leading the global scale-up and optimisation of the site payment reconciliation framework across BeOne clinical studies. This role serves as a key cross-functional partner driving payment transparency, operational efficiency, workflow optimisation, and data-driven reconciliation strategies across global clinical programs. The Manager will lead initiatives to identify reconciliation opportunities, establish scalable operational models, and implement sustainable processes supporting clinical trial execution across regions, countries, studies, and investigator sites. The role requires strong collaboration across Clinical Business Operations, Clinical Operations and Digital Clinical Operations within the Global Clinical Operations Department, Digital Solutions & Engineering within the Global Statistics & Data Science (GSDS) Department and the payment vendor(s). The Manager will act as a central liaison between business and technical stakeholders to support digitisation, automation, AI-enabled process enhancements, and data integration initiatives for clinical site payments. The successful candidate must possess a strong understanding of clinical operations, clinical trial payment workflows, data mapping principles, and operational process management. This individual is expected to demonstrate strategic thinking, strong organisational and project management capabilities, intellectual curiosity, change leadership, and the ability to influence cross-functional stakeholders globally. This role will also contribute to the evolution of the broader site payment operational model through continuous improvement initiatives, workflow redesign, process standardisation, and implementation of innovative operational solutions. Essential Functions of the Job: Cross-Functional Leadership & Collaboration Lead the global site payment reconciliation and optimisation strategy across clinical studies and regions. Partner closely with Global Clinical Operations study teams and country teams to support reconciliation activities and operational alignment. Collaborate with Site Payment, Site Contracts, Site Budget, and Data Hub teams within Clinical Business Operations to improve payment workflows and operational efficiency. Establish strong partnerships with Digital Solutions & Engineering and Digital Clinical Operations stakeholders to support system integration, digitisation, automation, and data utilisation initiatives. Serve as the primary business lead and subject matter expert for global site payment reconciliation activities and operational optimisation initiatives. Facilitate cross-functional discussions to identify operational gaps, risks, dependencies, and opportunities for scalable process improvements. Communicate project progress, risks, and strategic recommendations effectively to leadership and key stakeholders. Strategic Planning & Operational Optimisation Develop and execute a scalable global framework for site payment reconciliation across studies, countries, and investigator sites. Lead identification and prioritisation of target studies, countries, and sites for reconciliation initiatives in partnership with leadership. Evaluate current operational workflows and identify opportunities for optimisation, standardisation, automation, and digitisation. Support development of future-state operational models for site payment management and reconciliation processes. Drive continuous improvement initiatives focused on operational efficiency, payment transparency, compliance, and data integrity. Lead and support change management activities associated with evolving operational processes and technologies. Develop project plans, timelines, governance models, and communication strategies for reconciliation and optimisation initiatives. Mo