Senior Research Assistant

About the role

The people of Memorial Sloan Kettering Cancer Center (MSK) are united by a singular mission: ending cancer for life. Our specialized care teams provide personalized, compassionate, expert care to patients of all ages. Informed by basic research done at our Sloan Kettering Institute, scientists across MSK collaborate to conduct innovative translational and clinical research that is driving a revolution in our understanding of cancer as a disease and improving the ability to prevent, diagnose, and treat it. MSK is dedicated to training the next generation of scientists and clinicians, who go on to pursue our mission at MSK and around the globe. Memorial Sloan Kettering Cancer Center seeks Senior Research Assistant in New York, NY to coordinate the laboratory biobank, including the reception and banking of specimens derived from clinical practice or from an array of clinical trials being held in MSKCC, as well as processing of the clinical specimens for downstream applications including the development of patient-derived xenograft (PDX) models, single cell RNA/ATAC/DNA/CITE sequencing, spatial transcriptomics and flow cytometry. Coordinate with a multidisciplinary team involving different MSKCC core facilities, clinicians and research coordinators, and development and maintenance of reference databases. Coordinate with the pathology core at MSKCC for the performance of histology work (including embedding, sectioning, immunohistochemistry and review of tissue, and state-of-the art multiplexed imaging techniques). Employ novel technologies in the lab, including single cell nuclei sequencing of small biopsies and PDXs and simultaneous single nuclei RNA/ATACseq and single nuclei DNAseq on flash frozen tissue samples. Provide in-vivo experiment support, including preparing cells for injection into mice, and processing collected specimens for preservation for downstream molecular analyses (RNAseq, ATACseq, ChIPseq and proteomics). Lead independent research projects related to lung cancer therapeutics. Supervise, mentor, and train new recruits in molecular biology and cell culture techniques. Assist postdocs and Ph.D. students with molecular biology work, including Western Blots, routine cell culture work, FACS sorting, flow cytometry, plasmid amplification, and PCR. Acting as the safety manager of the laboratory by coordinating with the institutional Environmental, Health and Safey and ensuring the lab is compliant with safety standards. EEO/VETS/ADA.