Vice President, Gene Editing Core

Responsibilities

• Strategic Planning and Leadership: Creates and leads vision of genomics innovation to support research in developing gene-editing therapies
• Collaborates across Platform Innovation and Delivery Innovation to advance novel nucleases, insertion strategies, new technologies , delivery advancements, and develop assays to assess the potential for unintended genomic changes
• Supports Screening efforts generating data in support of advancing the pipeline programs and platform improvements including guide RNA, messenger RNA, and delivery optimization as well as novel nuclease advancement
• Oversees NGS production efforts, running AMP-seq, off-target discovery, off-target confirmation, and structural variant analysis
• Collaborates with Pre-Clinical NGS for assay transfer, validation, and scale-up
• Partners with computational biology, software engineering, and automation on data analysis, data capture, and workflow optimization
• Evaluat es and adopt s new technologies and platforms to improve methods and technology in support of the c ompany's strategic direction
• Oversee s the budget and resource allocation of the Genomics Core, including equipment purchases , ensuring timely delivery of services across all relevant company projects
• Ensur es proper documentation, sample tracking, compliance with regulations, guidelines, and standards related to genomic research, data management, and biosafety protocols
• Communicat es with users, providing guidance, and bringing in external consult ant and collaborators as needed
• Work s with clinical, regulatory, and product development teams to integrate gene editing and genomics insights into workflows, and other business processes
• Serve s as a functional representative for program teams, providing expertise and guidance on gene editing methods to support development candidate nomination and regulatory filing
• Foster s a culture of collaboration, innovation, teamwork, and communication, and handle discipline and termination of employees in accordance with company policy
• Supervisory Responsibilities
• Provide strategic direction and oversight to the C

Benefits

Additional Information

Why Join Intellia? Our mission is to develop curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases. Beyond our science, we live our four core values: One, Explore, Disrupt, Deliver and feel strongly that you can achieve more at Intellia. We have a single-minded determination to excel and succeed together. We believe in the power of curiosity and pushing boundaries. We welcome challenging thoughts and imagination to develop innovative solutions. And we know that patients are counting on us to make the promise a reality, so we must maintain high standards and get it done. We want all of our people to go beyond what is possible. We aren't constrained by typical end rails, and we aren't out to just "treat" people. We're all in this for something more. We're driven to cure and motivated for change. Just imagine the possibilities of what we can do together. Job Title Vice President, Gene Editing Core Job Summary The Vice President, Gene Editing Core l ead s a highly cross-functional team applying state-of-the-art genomic and molecular biology tools to advance genome editing therapies . This role will oversee the planning, execution, and delivery of projects to support early research and development studies , developing assays and reagents to characterize gene editing outcomes including on and off-target as well as structural variant assessment . T his leadership role s upport s the advancement of platform improvements and novel nucleases into therapeutic programs. This highly visible R&D cross functional leadership role is integral to advancing therapeutic programs and innovative platform solutions . He/she l ead s a team of scientists, provide s technical expertise and play s a key role in cross-functional collaboration and coordination to support the development of gen e editing-based therapeutics. This role will develop strategy, implement, and lead state-of-the-art genomics and RNA lab s , managing support for a portfolio of projects by develop ing and i mplement ing gene editing analysis technolog ies and platforms as well as gene editing component production (sgRNA, mRNA) and will work close together with project teams to drive the organization's discovery projects to development candidates . This role will also be responsible for driving the growth and success of the team, fostering a culture of collaboration and innovation, managing external collaborations, and ensuring the delivery of high-quality results that meet organizational goals. As a senior leader , this incumbent is responsible for driving the strategic vision and execution of gene editing initiatives within the company. In addition, this role will assess new technologies i n the genomics space and bring ing in new technologies as needed. Duties/Responsibilities

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