AbbVie Oncology Discovery is seeking a highly motivated and experienced cancer cell biologist to support drug discovery projects in our in vitro cancer biology team with a focus on antibody-drug conjugates. The candidate will work closely with a team of experienced scientists to develop and optimize key pharmacological, biochemical and cell-based assays to support multiple programs.
Responsibilities
Design and execute in vitro studies to assess novel antibody-drug conjugates
Analyze and interpret experiments and present data to the broader project team and group meetings. Propose relevant follow-up experiments as needed.
Troubleshoot and/or optimize experimental procedures as needed to further the program goals.
Contribute to the preparation of data packages for scientific publications, regulatory documents, and patent applications
Work independently in a fast paced, multi-tasking environment as part of a diverse research team.
Collaborate with cross-functional teams to advance programs from early discovery to preclinical development
Requirements
Required:
Bachelor's Degree with 5 years of experience, or Master's Degree with two years of experience in molecular/cellular biology, cancer biology, pharmacology or related discipline with significant research experience.
Proficiency in tissue culture, cellular & biochemical in vitro assay development and molecular biology techniques (e.g Western blotting/WES, ELISA, proliferation assays, FACS, lentivirus)
Background in drug discovery, pharmacology and assay development.
Organizational skills and experience with computer programs, including Microsoft Excel, Powerpoint, GraphPad, FlowJo, etc.
Preferred:
Understanding and application of methods of antibody characterization and/or antibody-drug conjugates.
Knowledge and experience with a broad range of assays to characterize targeted protein degradation
Familiarity and proficiency with available genomic/transcriptomic datasets (TCGA, DepMap, CCLE etc.)
Key Leadership Competencies:
Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance.
Learns fast, grasps the 'essence' and can change the course quickly where indicated.
Raises the bar and is never satisfied with the status quo.
Creates a learning environment, open to suggestions and experimentation for improvement.
Embraces innovation and manages to reality.
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our short-term incentive programs.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
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Abbvie · North Chicago, IL