Identify and develop products, workflows, and key culture optimizations (i.e. expansion, differentiation, and characterization) for stem cell-based therapy and organoid research and application.
Develop and optimize robust and reproducible cell differentiation protocols, analytical methods, and other processes needed to convert human induced pluripotent stem cells (iPSCs) into cellular products and therapeutics.
Lead core teams and collaborate with cross-functional teams to formulate cell differentiation reagents and protocols for different iPSC-derived cell types.
Serve as a subject matter expert in organoids, supporting new product initiatives including organoid model development, disease modeling applications, drug screening platforms, and protocol scale-up.
Develop cell-based, biochemical, and/or molecular assays to characterize the identity and physiology of stem cell-derived differentiated cells and organoids.
Plan and perform experiments, analyze data, and generate presentations to inform project progress to wider department and leadership.
Provide substantial, high-quality contributions to projects by working independently, communicating effectively within cross-functional team and leverage available expertise and support across the organization.
Contribute to corporate scientific activities/roadmaps/strategy.
Develop scientific content including conference presentations, publications, application notes, webinars and other Sales and Marketing efforts to support and promote Bio-Techne's stem cell, organoids, and regenerative medicine product offerings and services.
Apply scientific methods and process design principles to improve development, manufacturing and quality control processes.
Author documentation including standard operating procedures (including Manufacturing and QC) for RUO and GMP products, design verification and validation procedures, and technical reports to support lab operation, development initiatives, and product investigations.
Stay up to date with the latest scientific developments and market offerings in the fields of stem cell, organoids, and regenerative medicine.
Provide subject matter expertise, mentorship, and leadership to other scientists and research associates across the department and the wider Bio-Techne team.
Qualifications & Experience:
Ph.D. in Biology, Biomedical Engineering, Chemical Engineering, or a related field, with a minimum of 2+ years of industry experience in cell and gene therapy, regenerative medicine, or biomanufacturing.
The ideal candidate has translational research experience applying organoid models to disease biology, drug discovery, and/or therapeutic screening.
Proven expertise in process development for stem cell-based therapy research, including scaling workflows from discovery to GMP-compliant manufacturing.
Hands-on experience with adherent cell culture systems and advanced bioreactor platforms for large-scale cell expansion and differentiation.
Significant technical expertise/scientific knowledge of autologous or allogeneic cell therapies or differentiation pathways.
Expertise in fluorescence microscopy and standard cell characterization assays (e.g. RT-PCR, flow cytometry, ELISA, and ICC) required. High throughput assays or high content imaging experience strongl
Additional Information
By joining Bio-Techne, you'll join a company with a powerful and positive purpose of enabling cutting-edge research in Life Sciences and Clinical Diagnostics. Bio-Techne, and all of its brands, provides tools for researchers to further treat and prevent disease worldwide.
Pay Range:
$87,600.00 - $144,000.00 Senior Scientist, Regenerative Medicine - Customer Applications
Position Summary:
The Regenerative Medicine - Customer Applications Senior Scientist is a key member of a dynamic team focused on developing innovative products and applications for regenerative medicine and organoid research. We are seeking a highly skilled and experienced scientist with demonstrated expertise in diverse organoid workflows, disease modeling, and driving innovation for stem cell-derived therapies. The successful candidate will play a critical role in developing and improving human pluripotent stem cell (hPSC)-based differentiation and characterization techniques.
As a part of this role, you'll help drive significant progress in regenerative and personalized medicines by joining a collaborative team of innovators working to create impactful solutions for drug discovery and clinical trials. This position offers a unique opportunity to utilize the breadth of Bio-Techne's product portfolio and work closely with various teams to maximize the impact of our reagent solutions. Key responsibilities include developing products and applications for expansion, differentiation, and characterization of stem cell derived organoid models. Experience in culturing stem cells (e.g. iPSC, ESC, MSC or adult stem cells) and in 3D culture systems, including spheroid, organoids - is required.
Biotechne · Minneapolis, MN