Scientist/ Senior Research Officer, Bioinformatics, IHDP

About the role

The A*STAR Institute for Human Development and Potential (A*STAR IHDP) focuses on research that aims to improve and impact the health and well-being of Singaporeans across the life course. Job Description: Support the data management and data analytics deliverables for a cardiometabolic health study. The role focuses on data collection, monitoring, and multi-modal data integration, with a specific emphasis on Electronic Health Records (EHR), genetic/molecular epidemiologic research, and the application of Large Language Models (LLM) for data curation and analytics. Job Responsibilities: Apply advanced statistical and computational methods to analyze large datasets of protein or metabolite profiles. Implementation of effective data management processes across clinical, multi-omics, and wearables data in hybrid AWS cloud environment Apply Large Language Models (LLM) to extract, process, and analyze information from unstructured clinical notes and health records. Proactive quality control audits/quality management plans across longitudinal visits to ensure data accuracy, completeness, and proper usage of data management systems. Identify patterns, correlations, and predictive insights to assess patient risk stratification and disease progression. Job Requirements: PhD in Chemistry, Bioinformatics or Biomedical Engineering or a related field. A MSc or PhD in Data Science, Statistics, Mathematics, Computer Science, Physics or related quantitative field are also welcome to apply. Knowledge of genetic and molecular epidemiologic research (e.g., GWAS, polygenic risk scores, molecular data integration). Worked with EHR or observational human data (e.g., handling structured/unstructured data). Knowledge of or experience with Large Language Models (LLM) (e.g., prompt engineering, fine-tuning, or NLP for healthcare text), probabilistic modelling, transfer learning, programming in Python, R, or other languages.

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