Sr. Data Scientist AI/ML Drug Discovery - Onsite San Diego HQ

About the role

At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs. What We Do: Neurocrine Biosciences is a leading neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, neuroendocrine and neuropsychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, endometriosis* and uterine fibroids,* as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders because you deserve brave science. For more information, visit neurocrine.com , and follow the company on LinkedIn , X and Facebook . ( *in collaboration with AbbVie ) Leads the development and application of advanced AI/ML methods by using diverse multi-omics datasets to understand mechanisms of drug action and enhance drug discovery and development. This role focuses on building predictive and mechanistic models that directly inform target identification, molecular properties, and patient stratification, to generate actionable insights. This role emphasizes deploying AI/ML into real drug development pipelines, not just exploratory research. _ Your Contributions (include, but are not limited to): Design, develop, and deploy AI/ML models to support key drug development decisions, including target validation, mechanism-of-action modeling, biomarker discovery and patient stratification Build predictive and mechanistic models leveraging multi-modal datasets (genomics, transcriptomics, proteomics, scientific knowledge, and clinical data) Apply, expand, and validate state-of-the-art AI approaches including deep learning, transformers, and generative models Train and fine-tune AI models using internal datasets Translate complex biological datasets (e.g., scRNA-seq, spatial omics) into disease-relevant insights and hypotheses. Leverage these datasets to contextualize target gene expression in the context of cell types, disease biology and phenotypes Continuously refine processes and workflows to boost efficiency, effectiveness, and reproducibility of AI/ML solutions Build and implement AI/ML techniques to build pipelines for antibody design and optimization including structure prediction, sequence modeling and representation, affinity, selectivity, and drug-like properties Drive cross-functional initiatives to embed AI/ML into end-to-end drug discovery pipelines Stay current with industry trends and apply best practices to improve internal tools and processes Develop methods for integrating and visualizing multi-omics data Implement quality control measures and standard operating procedures Communicate findings to scientific and executive stakeholders, linking AI outputs to program-level decisions Stay updated with AI/ML advancements and drive accelerated internal innovations Other duties as assigned