Be responsible for developing chemical processes for the manufacturing of drug substances
Demonstrates technical knowledge, scientific creativity, and collaboration skills in the development and execution of research for the preparation of novel chemical substances
Plans, executes and analyzes laboratory experimentation to advance the knowledge of production and quality attributes of drug substances
Proposes alternative chemistry, including new route selection and step optimization
Provides regular updates to supervision and proposes future research directions
In collaboration with senior scientists, develops project strategy for manufacturing of drug substances to support clinical studies and commercialization
Responsible for the day to day management of project team members and research assignments, including designing and interpreting of experimentation
Prepares and reviews technical documents including research reports, process development reports, and documentation for the manufacturing of chemical substances e.g. Master Batch Records (MBRs)
Collaborates across functional areas including analytical chemistry, quality assurance, and manufacturing to accomplish project goals. Acts as a subject matter expert for cross-functional teams and research personnel
Provides technical support for manufacturing processes performed under cGMP in laboratory manufacturing and large-scale manufacturing operations
Ensures that all experimentation is carried out in accordance with appropriate standard operating procedures (SOPs), maintaining quality, safety, and environmental standards
Requirements
8+ Years with BS
OR
6+ Years with MS
0+ Years with PhD/PharmD
PhD in Organic Chemistry (or related discipline) and 2+ years of relevant experience minimum . We prefer a PhD with 2-10 years ideally, level will be commensurate with experience OR
MSc degree with extensive industry experience (6+ years) OR
BSc degree with extensive industry experience (8+ years)
Experience in planning and executing multi-step synthesis of organic molecules
Experience scaling up synthetic routes and developing safe pro
Benefits
Health insuranceVision insurance
Additional Information
At Gilead, we're creating a healthier world for all people. For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer - working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world's biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.
Every member of Gilead's team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we're looking for the next wave of passionate and ambitious people ready to make a direct impact.
We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together.
Job Description
At Gilead our pursuit of a healthier world for all people has yielded a cure for hepatitis C, revolutionary improvements in HIV treatment and prevention as well as advancements in therapies for viral and inflammatory diseases and certain cancers.
We set and achieve bold ambitions in our fight against the world's most devastating diseases, united in our commitment to confronting the largest public health challenges of our day and improving the lives of patients for generations to come.
This role is responsible for the development and optimization of chemical processes for the manufacture of drug substances supporting clinical and commercial programs. The scientist will plan, execute, and interpret laboratory experimentation to advance process understanding, product quality, and manufacturability, including route selection, step optimization, and scale‑up. Working collaboratively with senior scientists and cross‑functional partners, the role contributes to overall project strategy and provides technical leadership to project teams.
The position includes day‑to‑day oversight of research activities and project team members, preparation and review of technical documentation such as development reports and Master Batch Records, and hands‑on support of laboratory and large‑scale manufacturing activities conducted under cGMP. The successful candidate will act as a subject matter expert across functions, ensure compliance with safety, quality, and environmental standards, and demonstrate strong scientific judgment, communication, and leadership capabilities while operating in a collaborative, multidisciplinary environment.
Gilead Sciences · - California - Foster City