Sr. Director, Nonclinical Safety & Portfolio Strategy

External

Abbvie · North Chicago, IL

Full-timeOn-siteToday

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About the role

AbbVie's Development Biological Sciences department is seeking a Senior Director for its Portfolio Leadership Group. This pivotal leadership role will serve as a nonclinical safety representative for assigned molecules across AbbVie's diverse portfolio. As a safety representative, the Senior Director will be responsible for the overall strategy and execution of the nonclinical toxicology program, collaborating cross-functionally with project leads, providing data interpretation at various internal and external venues, and authoring regulatory documents. The ideal candidate will have 15+ years of experience in the area of non-clinical safety within the pharmaceutical industry. He/she should have the experience and ability to develop drug candidates from discovery through marketing. This senior-level position is expected to have a high impact contributing scientific expertise in nonclinical safety assessment, knowledge of industry best practices and pertinent regulatory guidelines, and a vision of future enhancements in the field.

Responsibilities

Drive the strategic vision and direction for nonclinical safety, influencing key R&D and portfolio decisions at the organizational level.

Serve as an active member for multi-disciplinary project teams as a nonclinical safety functional area subject matter expert.

Participate in due diligence reviews of drug products to identify potential risks and provide recommendations for partnership or in-licensing.

Author and submit regulatory documents (IBs, INDs/CTAs, NDAs/BLAs, regulatory queries) and interact with regulatory agencies (US and ex-US) as needed.

Generate impurity, excipient and metabolite risk assessments as necessary during the life cycle of a drug candidate.

Lead, mentor and develop others as it pertains to drug development and the execution of the portfolio, with an emphasis on the nonclinical aspects.

Participation in pharmaceutical industry consortia related to nonclinical aspects of drug development.

PhD or DVM required.

15+ years of relevant experience in pharmaceutical industry leading nonclinical safety programs.

Experience authoring relevant regulatory documents and responding to requests from regulatory agencies.

Deep expertise in a particular therapeutic area or modality (e.g. immunology, gene therapy, etc) is a benefit, but not required.

General awareness and understanding of drug metabolism and pharmacokinetics and its interplay with safety (e.g. MIST, drug-drug interactions, toxicokinetics, anti-drug antibodies...) is a plus.

Skilled in project/program management and leadership.

General computer skills and knowledge of the Microsoft applications including but not limited to Microsoft Word, Excel, and PowerPoint and applying AI as appropriate and necessary.

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.

This job is eligible to participate in our short-term incentive programs.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

Sr. Director, Nonclinical Safety & Portfolio Strategy

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