MD with 6 + years of drug development industry experience .
Board eligibility/certification and clinical experience in internal medicine and/or pediatrics. Additional clinical or research experience in nephrology or cardiometabolic diseases is preferred.
E xperience as a clinical study medical monitor
Experience with the preparation and submission of scientific publications, study protocols , Investigator Brochures , and other clinical-regulatory documents.
Experience in the planning and oversight of early-stage and/or registration-enabling clinical development programs including CRO and site selection and relationship building with investigators/site study staff, patient advocacy groups, and other third parties
Demonstrated knowledge and experience in the desig n and conduct of clinical trials and clinical data analysis and interpretation , particularly Phase 2 trials .
Experience leading a cross-functional study team.
Committed to nurturing relationships with investigators, site study staff, patient advocacy groups, and other third parties to support the clinical programs and broader Maze objectives .
Exceptional organizational, analytical, and communication skills, enabling you to translate corporate objectives into actionable plans that consistently deliver high-quality data on time and withi
Benefits
Health insurance
Additional Information
The Position
At Maze Therapeutics, we are assembling a team of passionate, creative, and dedicated professionals to join us on our mission to turn groundbreaking genetic discoveries into life-saving medicines. We're looking for a Senior Medical Director to join our Clinical Sciences team and take a central role in pioneering the future of healthcare.
As a Senior Medical Director, you'll be at the forefront of translating genetic insights into innovative treatments for patients . Your work will help drive the clinical development programs for game-changing therapies, starting with a small molecule that targets SLC6A19 - a novel therapeutic target for the treatment of chronic kidney disease and phenylketonuria .
Maze Therapeutics has an exciting pipeline spanning both rare and common renal, cardiac, and metabolic diseases. In short, you'll play a fundamental part in advancing medical breakthroughs that have the potential to transform many lives.
To succeed in this role, you'll need to thrive in a fast-paced, collaborative environment. As a Senior Medical Director for one or more development programs, you will partner closely with cross-functional team members and other technical experts to design, conduct, and interpret the key clinical studies, including first-in-human and proof-of-concept trials. Your contributions will be highly visible and integral to the success of the Maze team.
This position reports to the Head of Clinical Development .
The Impact You'll Have
Lead the design, execution, and analysis of clinical trials for the SLC6A19 program and other early-stage clinical assets at Maze
Author and review clinical-regulatory documents, including protocols and amendments, informed consents, study reports, and SAPs
Prepare and deliver scientific presentations and other communication materials for internal and external stakeholders, including investigators and other Maze collaborators.
Engage with scientific thought leaders and patient advocacy groups to gain insights to inform clinical development plans and build awareness and enthusiasm for the Maze pipeline assets .
Partner with Clinical Development Operations to identify and select study investigators and sites and b uild strong professional relationships with study investigators.
Partner with Clinical Development Operations to identify , select, and oversee vendors and CROs to support program needs .
Develop and integrate timelines and budgets for clinical activities with overall company timelines and goals, in close coordination with project management, CMC, nonclinical development, regulatory affairs, and other stakeholders .
As a Senior Director , we also expect our leaders to demonstrate the following Leadership Competencies:
Communication and Influence
Builds communication channels across Maze for sharing information.
Influences Senior Management decisions through persuasive arguments.
Respectfully addresses differing opinions leading to support of decisions.
Teamwork and Collaboration
Champions partnerships and connections across Maze.
Proactively addresses issues that could result in breakdown of team relationships.
Spotlights team and individual contributions in public forums.
Execution and Results
Addresses gaps and leverages strengths to get best results.
Maintains a steadying presence and clarifies priorities during change.
Anticipates and removes barriers that put functional/corporate goals at risk.
Develop Others and Self
Remove barriers to staff development and empowers them to make their own decisions.
Stays current on industry trends and keeps direct-reports prepared and responsive.
Mazetherapeutics · South San Francisco, CA