Advisor - Antibody Developability Validation & Benchmarking

Responsibilities

• Statistical Rigor : Design statistically powered validation studies that account for multiple testing across endpoints, hierarchical structure in antibody data (sequences clustered by germline, project, partner), and non-independent observations. Provide honest confidence

Benefits

Additional Information

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world. O rganization Overview At Lilly, we serve an extraordinary purpose. We make a difference for people around the glob e by discovering, developing and delivering medicines that help them live longer, healthier, more active lives. Not only do we deliver breakthrough medications, but you also can count on us to develop creative solutions to support communities through philanthropy and volunteerism. Purpose Lilly TuneLab is an AI-powered drug discovery platform that provides biotech companies with access to machine learning models trained on Lilly's extensive proprietary pharmaceutical research data. Through federated learning, the platform enables Lilly to build models on broad, diverse datasets from across the biotech ecosystem while preserving partner data privacy and competitive advantages. Antibody developability prediction is a core workstream within TuneLab - covering aggregation, self-association, polyspecificity, thermal stability, viscosity, and chemical liabilities - that gates progression from discovery into lead optimization, cell line development, and formulation. The Advisor/Senior Advisor - Antibody Developability Validation & Benchmarking plays an essential role in establishing whether TuneLab's federated antibody models can be trusted to triage real candidates. The person in this seat must understand, at depth, how antibodies are characterized, what makes a sequence developable or not, and how predictions from a federated model translate into go/no-go decisions in a discovery pipeline. This is a validation-led role that contributes to model design choices. The person will partner closely with antibody modeling scientists on architecture, feature design, and uncertainty quantification - not just downstream of them.